Evidence map›Paper›PMID 41413254›Full record

ArticleNPJ digital medicine2025

Effects of app delivered self hypnosis on stress management.

Nathan Tran, Corey Saperia, Eric Neri, Booil Jo, Bohye Kim, Nahom Zewde, Bita Nouriani, Cassidy Kinderman, Annemarie Jagielo, Afik Faerman and 2 more

Abstract read
In one paragraph

Article in NPJ digital medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Nathan Tran *Department of Psychiatry & Behavioral Sciences, School of Medicine, Stanford University, Stanford, CA, USA.
Corey Saperia *Department of Psychiatry & Behavioral Sciences, School of Medicine, Stanford University, Stanford, CA, USA.
Eric NeriDepartment of Psychiatry & Behavioral Sciences, School of Medicine, Stanford University, Stanford, CA, USA.
Booil JoDepartment of Psychiatry & Behavioral Sciences, School of Medicine, Stanford University, Stanford, CA, USA.
Bohye KimDepartment of Psychiatry & Behavioral Sciences, School of Medicine, Stanford University, Stanford, CA, USA.
Nahom ZewdeSchool of Medicine, University of Pittsburgh, Pittsburgh, PA, USA.
Bita NourianiDepartment of Psychiatry & Behavioral Sciences, School of Medicine, Stanford University, Stanford, CA, USA.
Cassidy KindermanDepartment of Psychiatry & Behavioral Sciences, School of Medicine, Stanford University, Stanford, CA, USA.
Annemarie JagieloDepartment of Psychiatry & Behavioral Sciences, School of Medicine, Stanford University, Stanford, CA, USA.
Afik FaermanDepartment of Psychiatry & Behavioral Sciences, School of Medicine, Stanford University, Stanford, CA, USA.
Jose MaldonadoDepartment of Psychiatry & Behavioral Sciences, School of Medicine, Stanford University, Stanford, CA, USA.
David SpiegelDepartment of Psychiatry & Behavioral Sciences, School of Medicine, Stanford University, Stanford, CA, USA. dspiegel@stanford.edu.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Stress and stress-related chronic illness are increasing worldwide while mental health care access remains limited. Recent neurophysiological advances support the effectiveness and safety of hypnosis for stress management. In this retrospective observational study, we studied app-delivered hypnosis in 84,395 users across 282,893 stress reduction sessions. Users rated pre- and post-session stress on a 10-point Likert Scale. Data analysis utilized Linear Mixed Effects (LME) models to accommodate repeated measures and missing data. Effects of session type, user hypnotizability, age, sex, and membership were assessed. Pre-to-post stress reduction occurred consistently in each of the first 10 sessions (Cohen's d values ranging from -0.71 to -0.78), demonstrating significant improvement in stress management. Across the first 10 sessions, greater stress reduction was observed with interactive and regular-length sessions, higher hypnotizability, older age groups, and paying members. Findings provide evidence that disseminable digital formulations of hypnosis contribute meaningfully to stress reduction.

Identifiers

PMID41413254
PMCPMC12775527

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.