Evidence map›Paper›PMID 41413170›Full record

ArticleNPJ digital medicine2025

Personalizing prostate cancer education for patients using an EHR-Integrated LLM agent.

Yuexing Hao, Jason Holmes, Mark R Waddle, Brian J Davis, Nathan Y Yu, Kristin S Vickers, Heather Preston, Drew Margolin, Corinna E Löckenhoff, Aditya Vashistha and 3 more

Abstract read
In one paragraph

Article in NPJ digital medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. Article
  4. Article
  5. Experiences of mHealth use in head and neck cancer care: a thematic synthesis guided by the Unified Theory of Acceptance and Use of Technology.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026
    Review
  6. Review
  7. Article
  8. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Yuexing HaoCornell University, Ithaca, NY, USA. yh727@cornell.edu.
Jason HolmesDepartment of Radiation Oncology, Mayo Clinic, Phoenix, AZ, USA.
Mark R WaddleDepartment of Radiation Oncology, Mayo Clinic, Rochester, MN, USA.
Brian J DavisDepartment of Radiation Oncology, Mayo Clinic, Rochester, MN, USA.
Nathan Y YuDepartment of Radiation Oncology, Mayo Clinic, Phoenix, AZ, USA.
Kristin S VickersDepartment of Radiation Oncology, Mayo Clinic, Rochester, MN, USA.
Heather PrestonDepartment of Radiation Oncology, Mayo Clinic, Rochester, MN, USA.
Drew MargolinCornell University, Ithaca, NY, USA.
Corinna E LöckenhoffCornell University, Ithaca, NY, USA.
Aditya VashisthaCornell University, Ithaca, NY, USA.
Saleh KalantariCornell University, Ithaca, NY, USA.
Marzyeh GhassemiDepartment of Electrical Engineering and Computer Science, Massachusetts Institute of Technology, Cambridge, MA, USA.
Wei LiuDepartment of Radiation Oncology, Mayo Clinic, Phoenix, AZ, USA. liu.wei@mayo.edu.

Funding

Dose Linear Energy Transfer Volume Histogram and Dosimetric Seed Spot Analysis in Spot Scanning Proton TherapyR01CA280134 · NCI · MAYO CLINIC ARIZONA · PI Wei Liu · 2024 to 2026
$1.7M
NCI NIH HHS R01 CA280134NCI NIH HHS R01CA280134
6 · The paper itself

Abstract

Cancer patients often lack timely education and personalized support due to clinician workload. This quality improvement study develops and evaluates a Large Language Model (LLM) agent, MedEduChat, which is integrated with the clinic's electronic health records (EHR) and designed to enhance prostate cancer patient education. Fifteen non-metastatic prostate cancer patients and three clinicians recruited from the Mayo Clinic interacted with the agent between May 2024 and April 2025. Findings showed that MedEduChat has a high usability score (UMUX = 83.7/100) and improves patients' health confidence (Health Confidence Score rose from 9.9 to 13.9). Clinicians evaluated the patient-chat interaction history and rated MedEduChat as highly correct (2.9/3), complete (2.7/3), and safe (2.7/3), with moderate personalization (2.3/3). This study highlights the potential of LLM agents to improve patient engagement and health education.

Identifiers

PMID41413170
PMCPMC12714722

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.