Evidence map›Paper›PMID 41413153›Full record

ArticleScientific reports2025

Advanced ANN-LMB modeling of hepatitis B transmission across sexual networks and its disability burden.

Rahat Zarin, Kamel Guedri, Basim M Makhdoum, Hatoon A Niyazi, Bandar M Fadhl, Hamiden Abd El-Wahed Khalifa

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Rahat ZarinDepartment of Mathematics, Faculty of Science, King Mongkut's University of Technology, Thonburi (KMUTT), Bangkok, 10140, Thailand. rahatmathematicion@gmail.com.
Kamel GuedriMechanical Engineering Department, College of Engineering and Architecture, Umm Al-Qura University, P. O. Box 5555, 21955, Mecca, Saudi Arabia.
Basim M MakhdoumMechanical Engineering Department, College of Engineering and Architecture, Umm Al-Qura University, P. O. Box 5555, 21955, Mecca, Saudi Arabia.
Hatoon A NiyaziDepartment of Clinical Microbiology and Immunology, Faculty of Medicine, King Abdulaziz University, 21589, Jeddah, Saudi Arabia.
Bandar M FadhlMechanical Engineering Department, College of Engineering and Architecture, Umm Al-Qura University, P. O. Box 5555, 21955, Mecca, Saudi Arabia.
Hamiden Abd El-Wahed KhalifaDepartment of Operations and Management Research, Faculty of Graduate Studies for Statistical Research, Cairo University, Giza, 12613, Egypt.

Funding

King Salman Center for Disability Research, Riyadh 11614, Saudi Arabia KSRG-2024-184
6 · The paper itself

Abstract

Hepatitis B virus (HBV) remains a major global health concern, with sexual transmission being a key driver among adults. This study develops a gender-stratified compartmental model of HBV spread that integrates long-term disability through gender-specific parameters. A key contribution is the integration of mechanistic modeling with artificial neural networks (ANNs), enabling efficient emulation of the model's nonlinear dynamics. Numerical solutions from the classical Runge-Kutta 4th-order (RK4) method were used as training data for an ANN optimized with the Levenberg-Marquardt algorithm (ANN-LMB). The trained ANN accurately reproduces compartmental dynamics with minimal error and provides a fast surrogate for sensitivity exploration. Analysis of the basic reproduction number ([Formula: see text]) reveals the strong influence of same-sex transmission rates, contact patterns, and disability onset parameters. These findings highlight the importance of behavioral interventions, vaccination coverage, and early detection of chronic carriers. Overall, the proposed ANN-LMB framework enhances computational efficiency and offers a biologically informed approach for exploring complex HBV transmission dynamics.

Indexed as

Hepatitis BNeural Networks, ComputerAdultAlgorithmsBasic Reproduction NumberFemaleHepatitis B virusHumansMalePersons with DisabilitiesSexual BehaviorArtificial neural networksDisability modelingEpidemiological forecastingParameter sensitivitySexual transmission

Identifiers

PMID41413153
PMCPMC12727733

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.