Evidence map›Paper›PMID 41413125›Full record

ArticleScientific reports2025

Rapid potentiometric and spectrophotometric determination of cefotaxime in pharmaceutical and biological samples.

Badriah Saad Al-Farhan, Ahmed H Naggar, Othman A Farghaly

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Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Badriah Saad Al-FarhanChemistry Department, Faculty of Girls for Science, King Khalid University, Abha, Kingdom of Saudi Arabia. bfrhan@kku.edu.sa.
Ahmed H NaggarDepartment of Chemistry, College of Science, Jouf University, Sakaka, Aljouf, 72341, Saudi Arabia. ahayoub@ju.edu.sa.
Othman A FarghalyDepartment of Chemistry, Faculty of Science, Al-Baha University, Al-Baha, Saudi Arabia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Simple, precise, rapid, and low-cost potentiometric and spectrophotometric methods were developed for the determination of cefotaxime in pure form, pharmaceutical formulations, and biological samples (urine and serum samples). The potentiometric method is based on the direct titration of cefotaxime in an aqueous medium with 0.1 M NaOH at µ = 0.5 NaCl and 25 ± 1.0 ℃ utilizing a combined glass pH electrode. Using the standard addition method based on Gran plot, the lower limits of detection and quantification were found to be 2.89 and 4.0 µg/mL, respectively over a linear concentration range of 4.0 to 65.0 µg/mL of cefotaxime with correlation coefficient of R

Indexed as

Anti-Bacterial AgentsCefotaximeHumansHydrogen-Ion ConcentrationLimit of DetectionPotentiometrySpectrophotometryAnti-Bacterial AgentsCefotaximeBiological fluidsCefotaximePharmaceutical formulationsPotentiometryPrussian blueSpectrophotometry

Identifiers

PMID41413125
PMCPMC12800039

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.