ArticleScientific reports2025
Liposomal co-delivery of β-carotene and doxorubicin for enhanced colorectal-cancer therapy.
Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
4 citing papers in PubMed.
- Food-Derived Natural Compounds as Molecular Targets in Cancer Prevention.Pharmaceutics · 2026Review
- Structural characterization and bioaccessibility of nanoliposomal lutein from pumpkin extract.Scientific reports · 2026Article
- Next-generation nanomedicine for cancer therapy: advances, challenges, and future perspectives.Frontiers in chemistry · 2026Review
- Physicochemical design of nanobiomaterials in oncology: structure-to-function principles for sequential transport and delivery.Frontiers in oncology · 2026Review
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Authors and funding
5 authors.
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No grant is acknowledged in the PubMed record.
Abstract
Colorectal cancer (CRC) remains a major cause of cancer-related mortality, motivating delivery systems that retain antitumor activity while limiting off-target toxicity. We engineered neutral multilamellar soy-lecithin liposomes co-encapsulating β-carotene (BC) and doxorubicin (DOX). Thin-film hydration produced vesicles with a DLS Z-average of 122.4 ± 83.4 nm (PDI = 0.534) and ζ-potential of - 25.6 ± 8.0 mV, and a TEM diameter of 184 ± 34 nm, with > 90% entrapment efficiency for both cargos. In HCT-116 cells the formulation preserved DOX potency (IC₅₀, µg mL⁻
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