Evidence map›Paper›PMID 41413085›Full record

ArticleScientific reports2025

A multi-task learning model for evaluating non-tumor gastric diseases indicators in whole slide images.

Mingxi Fu, Liming Liu, Fanglei Fu, Jingli Ouyang, Xueying Shi, Song Duan, Tian Guan, Yonghong He, Zhiqiang Cheng, Lianghui Zhu

Abstract read
In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Mingxi FuShenzhen International Graduate School, Tsinghua University, Shenzhen, 518055, China.
Liming LiuDepartment of Pathology, The Second Affiliated Hospital of Southern University of Science and Technology (Shenzhen Third People's Hospital), Shenzhen, 518000, China.
Fanglei FuShenzhen International Graduate School, Tsinghua University, Shenzhen, 518055, China.
Jingli OuyangShenzhen International Graduate School, Tsinghua University, Shenzhen, 518055, China.
Xueying ShiDepartment of Pathology, School of Basic Medical Sciences, Peking University Third Hospital, Peking University Health Science Center, Beijing, 100083, China.
Song DuanDepartment of Pathology, Chongqing University Affiliated Three Gorges Hospital, Chongqing, 404000, China.
Tian GuanShenzhen International Graduate School, Tsinghua University, Shenzhen, 518055, China.
Yonghong He *Shenzhen International Graduate School, Tsinghua University, Shenzhen, 518055, China. heyh@sz.tsinghua.edu.cn.
Zhiqiang Cheng *Department of Pathology, The Second Affiliated Hospital of Southern University of Science and Technology (Shenzhen Third People's Hospital), Shenzhen, 518000, China. chengzhiqiang2004@aliyun.com.
Lianghui Zhu *Shenzhen International Graduate School, Tsinghua University, Shenzhen, 518055, China. zhulh@mails.tsinghua.edu.cn.

Funding

National Natural Science Foundation of China 82430062Shenzhen Engineering Research Center XMHT20230115004
6 · The paper itself

Abstract

Inflammation, acute activity, intestinal metaplasia, and atrophy are key indicators in gastric biopsy evaluations, with their grading being crucial for assessing gastric cancer progression. However, diagnostic subjectivity among pathologists and the complex interrelationships between these indicators present significant challenges. Additionally, the high resolution of whole slide images (WSIs) complicates large-scale annotation efforts. To address these issues, we propose a multi-task learning model utilizing self-supervised pre-trained weights from extensive pathological datasets. The model integrates four indicators-severity of inflammation, atrophy, acute activity, and intestinal metaplasia-training on WSIs to predict these indicators while accounting for their interrelationships. Our results show that multi-task learning outperforms single-task models, achieving higher accuracy across all indicators. This model can thus serve as an auxiliary tool for evaluating non-tumor gastric diseases and supporting diagnosis.

Indexed as

Image Processing, Computer-AssistedMachine LearningStomach DiseasesAtrophyBiopsyHumansMetaplasiaStomach Neoplasms

Identifiers

PMID41413085
PMCPMC12717044

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.