Evidence map›Paper›PMID 41413078›Full record

ArticleScientific reports2025

Biomechanical analysis of femoral component malalignment in medial unicompartmental knee arthroplasty.

Fangxing Wang, Jie Zhao, Weijie He, Huazheng He, Qiang Wang

Abstract read
In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Fangxing WangDepartment of Orthopaedic Surgery, The First Affiliated Hospital of Wannan Medical College, Wuhu city, Anhui Province, People's Republic of China.
Jie ZhaoDepartment of Orthopaedic Surgery, The First Affiliated Hospital of Wannan Medical College, Wuhu city, Anhui Province, People's Republic of China.
Weijie HeDepartment of Center of Precision Medicine, The First Affiliated Hospital of Wannan Medical College, Yijishan Hospital, Wuhu city, Anhui Province, People's Republic of China.
Huazheng HeDepartment of Orthopaedic Surgery, The First Affiliated Hospital of Wannan Medical College, Wuhu city, Anhui Province, People's Republic of China.
Qiang WangDepartment of Orthopaedic Surgery, The First Affiliated Hospital of Wannan Medical College, Wuhu city, Anhui Province, People's Republic of China. yjsgjgkwq1@163.com.

Funding

Major Project of Scientific Research Project of Provincial Education Department of Anhui Province 2022AH040170
6 · The paper itself

Abstract

Knee osteoarthritis (KOA) has a high prevalence among the elderly, severely affecting their quality of life and imposing a considerable burden on social health insurance. Unicompartment knee arthroplasty (UKA) continues to be favored by clinicians as a minimally invasive procedure. Fixed-bearing prostheses require more precision than mobile-bearing prostheses, and fewer studies have been done on the biomechanics of their misalignment. To evaluate the biomechanical consequences of this misalignment under different conditions, gain insight into these effects, and offer clinical recommendations, a standard knee model and several femoral prosthesis deviation types were created and evaluated. The evaluation indicators include the focus on the upper surface of the polyethylene (PE) insert, the tibial cartilage surface, as well as the medial and lateral collateral ligaments (MCL and LCL). Lateral translation of the femoral component center resulted in an 8.96% increase in maximum contact stresses (MCS) on the PE insert with a 5 mm deviation. Both varus and valgus alignments increased MCS on the PE insert, an increase of 11.34 and 12.46% for varus and valgus angles of 5°, respectively. For the tibial cartilage in the lateral compartment, MCS decreased with lateral movement of the femoral component center (standard position vs. 5 mm translation, 7.02 vs. 6.59 MPa) and increased with medial movement (standard position vs. 5 mm shift, 7.82 vs. 6.59 MPa). Stresses on the MCL increased with medial translation and valgus orientation of the femoral prosthesis, whereas stresses on the LCL increased with varus orientation and lateral translation of the femoral prosthesis. Surgeons should be vigilant about femoral prosthesis alignment, particularly when deviations exceed 5° or 5 mm, as such misalignments can lead to increased contact stresses and potential complications.

Indexed as

Arthroplasty, Replacement, KneeBone MalalignmentFemurKnee ProsthesisOsteoarthritis, KneeBiomechanical PhenomenaHumansKnee JointProsthesis DesignBiomechanical effectsFemoral prosthesisFinite element analysisMalalignmentUnicompartmental knee arthroplasty

Identifiers

PMID41413078
PMCPMC12714778

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.