Evidence map›Paper›PMID 41413076›Full record

ArticleScientific reports2025

Disassociating cerebral vasomotion from low frequency spontaneous neurovascular coupling.

Runchong Wang, Priya Patel, Luke Boorman, Michael Okun, Clare Howarth, Jason Berwick

Abstract read
In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Runchong Wang *School of Psychology, University of Sheffield, Sheffield, UK.
Priya Patel *School of Psychology, University of Sheffield, Sheffield, UK.
Luke BoormanOpteran, Sheffield, UK.
Michael OkunSchool of Psychology, University of Sheffield, Sheffield, UK.
Clare HowarthSchool of Psychology, University of Sheffield, Sheffield, UK.
Jason BerwickSchool of Psychology, University of Sheffield, Sheffield, UK. j.berwick@sheffield.ac.uk.

Funding

Medical Research Council UK grant [Grant number MR/M013553/1]
6 · The paper itself

Abstract

Vasomotion, vascular oscillations at ~ 0.1 Hz, may serve as a biomarker and therapeutic target for neurodegenerative diseases, but its origins, structure across brain vasculature, and correlation with neural activity remain unclear. This study examined the spatiotemporal characteristics of cerebral vasomotion and its relationship to neural activity in anaesthetised Hooded Lister rats using simultaneous recordings of neuronal activity and haemodynamics in motor and whisker barrel cortices. In a subset of rats, tissue oxygen was also measured. Blood pressure was pharmacologically modulated to alter vascular oscillations. We found that vasomotion was driven by the arterial tree. Two prominent activity patterns emerged: fast vasomotion across the entire hemisphere and slow vasomotion seen as a travelling wave running through the surface arteries. Moreover, vasomotion was associated with low tissue oxygen and was largely independent of spontaneous neural activity and therefore not a product of neurovascular coupling.

Indexed as

BrainCerebrovascular CirculationNeurovascular CouplingAnimalsBlood PressureHemodynamicsMaleNeuronsOxygenRatsOxygen

Identifiers

PMID41413076
PMCPMC12715225

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.