Evidence map›Paper›PMID 41413034›Full record

ArticleNature communications2025

Molecular insights into ligand recognition and signaling of OXGR1.

Aijun Liu, Yezhou Liu, Yuanzhengyang Long, Richard D Ye

Abstract read
In one paragraph

Article in Nature communications, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Aijun Liu *The Affiliated Dongguan Songshan Lake Central Hospital, Guangdong Medical University, Dongguan, Guangdong, China. liuaijun@cuhk.edu.cn.ORCID http://orcid.org/0009-0003-1636-3519
Yezhou Liu *Kobilka Institute of Innovative Drug Discovery, School of Medicine, The Chinese University of Hong Kong, Shenzhen, Guangdong, China.ORCID http://orcid.org/0000-0001-7575-8260
Yuanzhengyang LongKobilka Institute of Innovative Drug Discovery, School of Medicine, The Chinese University of Hong Kong, Shenzhen, Guangdong, China.ORCID http://orcid.org/0009-0009-7909-3230
Richard D YeKobilka Institute of Innovative Drug Discovery, School of Medicine, The Chinese University of Hong Kong, Shenzhen, Guangdong, China. richardye@cuhk.edu.cn.ORCID http://orcid.org/0000-0002-2164-5620

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

GPR99/OXGR1 is a G protein-coupled receptor (GPCR) with two endogenous agonists, the tricarboxylic acid cycle derivative 2-oxoglutarate (α-ketoglutarate) and the inflammatory mediator cysteinyl leukotriene E4 (LTE

Indexed as

Ketoglutaric AcidsReceptors, G-Protein-CoupledBinding SitesCryoelectron MicroscopyHEK293 CellsHumansLigandsModels, MolecularProtein BindingSignal TransductionKetoglutaric AcidsLigandsReceptors, G-Protein-Coupled

Identifiers

PMID41413034
PMCPMC12714840

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.