ReviewNature communications2025
Nanogels with volume phase transition for biomedical applications.
Review in Nature communications, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
4 citing papers in PubMed.
- Mechano-reprogramming of tumor-associated macrophages by engineering nanogel stiffness for suppression of tumor development.Journal of nanobiotechnology · 2026Article
- Precision Temperature Control of Volume Phase Transition in Biocompatible PEG-Based Nanogels for Triggered Drug Release.ACS nano medicine · 2026Article
- Structural Design of a Nanogel Reaction Device with Emphasis on Temperature-Field Uniformity.Materials (Basel, Switzerland) · 2026Article
- Nanogel-Based Precision Bone Regeneration: Rational Design, Biological Barrier Penetration, and Osteoporotic Microenvironment Remodeling.International journal of nanomedicine · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Nanogels, of which the three-dimensional network structures are covalently crosslinked by crosslinkers and supported by large number of hydrogen bonds, present unique volume phase transition (VPT) and play significant roles in multiple biomedical applications. Based on hydrogen bonds, the VPT features including the shift, sharpness, and range of VPT, can be rationally designed and precisely controlled by simply regulating the monomer, comonomer, crosslinker, structure, deuteration, environmental stimuli, and so on, for tailored biomedical applications such as transcatheter arterial embolization (TAE) and tumor targeting drug delivery (TTDD). Moreover, the exploration of the minimum value of physicochemical properties around volume phase transition temperature (VPTT) exhibits great potential in improving current tumor therapies and developing more therapeutic strategies. Integrating systematic knowledge of nanogel VPT properties, we provide the guidance for rational design of nanogels with tailored biomedical applications.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.