Evidence map›Paper›PMID 41413017›Full record

ReviewCell death & disease2025

NSUNs-driven dysregulation: the next frontier in targeted cancer therapy?

Yingqi Zhao, Yuying Zhang, Haonan Zhou, Lei Zhang, Jinyu Guo, Yue Tan, Ting Wu, Yi Peng, Ying Che, Zhanlei Pei and 6 more

Abstract readReview
In one paragraph

Review in Cell death & disease, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Yingqi Zhao *Department of Pharmacology, School of Pharmacy, China Medical University, Shenyang, PR China.
Yuying Zhang *Department of Pharmacology, School of Pharmacy, China Medical University, Shenyang, PR China.ORCID http://orcid.org/0009-0007-5204-5090
Haonan Zhou *Hepatobiliary Surgery Department, First Hospital of China Medical University, Shenyang, Liaoning Province, PR China.
Lei Zhang *Department of Pharmacology, School of Pharmacy, China Medical University, Shenyang, PR China.
Jinyu GuoDepartment of Pharmacology, School of Pharmacy, China Medical University, Shenyang, PR China.
Yue TanDepartment of Pharmacology, School of Pharmacy, China Medical University, Shenyang, PR China.
Ting WuDepartment of Pharmacology, School of Pharmacy, China Medical University, Shenyang, PR China.ORCID http://orcid.org/0009-0002-5402-2275
Yi PengDepartment of Pharmacology, School of Pharmacy, China Medical University, Shenyang, PR China.
Ying CheDepartment of Pharmacology, School of Pharmacy, China Medical University, Shenyang, PR China.
Zhanlei PeiDepartment of Pharmacology, School of Pharmacy, China Medical University, Shenyang, PR China.
Jun LiDepartment of Pharmacology, School of Pharmacy, China Medical University, Shenyang, PR China.
Boshi FuDepartment of Pharmacology, School of Pharmacy, China Medical University, Shenyang, PR China.
Minjie WeiDepartment of Pharmacology, School of Pharmacy, China Medical University, Shenyang, PR China. mjwei@cmu.edu.cn.
Gang WuHepatobiliary Surgery Department, First Hospital of China Medical University, Shenyang, Liaoning Province, PR China. gangw@cmu.edu.cn.
Xiaoyun HuDepartment of Pharmacology, School of Pharmacy, China Medical University, Shenyang, PR China. huxy2022@cmu.edu.cn.
Huizhe WuDepartment of Pharmacology, School of Pharmacy, China Medical University, Shenyang, PR China. wuhz@cmu.edu.cn.ORCID http://orcid.org/0000-0001-7964-1342

Funding

China Postdoctoral Science Foundation 2023MD734246China Postdoctoral Science Foundation 2025T180577National Natural Science Foundation of China (National Science Foundation of China) 82272915National Natural Science Foundation of China (National Science Foundation of China) 82573677
6 · The paper itself

Abstract

Epitranscriptomic modifications represent a fundamental regulatory layer in cancer biology, with RNA methylation emerging as a pivotal mechanism governing transcriptomic dynamics. Among these, 5-methylcytosine (m

Indexed as

MethyltransferasesMolecular Targeted TherapyNeoplasms5-MethylcytosineAnimalsEpigenesis, GeneticGene Expression Regulation, NeoplasticHumans5-MethylcytosineMethyltransferases

Identifiers

PMID41413017
PMCPMC12728181

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.