Evidence map›Paper›PMID 41411338›Full record

ArticlePloS one2025

Co-isolation of genetically distinct Burkholderia pseudomallei strains from a single patient in North Queensland.

Pauline M L Coulon, Piklu Roy Chowdhury, Ian Gassiep, Kay Ramsay, Aven Lee, Edita Ritmejeryte, Miranda E Pitt, Joyce To, Sarah Reed, Patrick N A Harris and 1 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in PloS one, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Profiling ofMicrobiology spectrum · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Pauline M L CoulonFaculty of Science, Australian Institute for Microbiology and Infection, University of Technology Sydney, Ultimo, New South Wales, Australia.ORCID https://orcid.org/0000-0001-9482-2360
Piklu Roy ChowdhuryFaculty of Science, Australian Institute for Microbiology and Infection, University of Technology Sydney, Ultimo, New South Wales, Australia.
Ian GassiepFaculty of Health, The University of Queensland Centre for Clinical Research (UQCCR), Medicine and Behavioural Sciences, The University of Queensland, St Lucia, Queensland, Australia.ORCID https://orcid.org/0000-0003-3548-6963
Kay RamsayFaculty of Health, The University of Queensland Centre for Clinical Research (UQCCR), Medicine and Behavioural Sciences, The University of Queensland, St Lucia, Queensland, Australia.
Aven LeeMass Sperectometry Facility, The University of Queensland Centre for Clinical Research (UQCCR), Medicine and Behavioural Sciences, The University of Queensland, St Lucia, Queensland, Australia.
Edita RitmejeryteMass Sperectometry Facility, The University of Queensland Centre for Clinical Research (UQCCR), Medicine and Behavioural Sciences, The University of Queensland, St Lucia, Queensland, Australia.
Miranda E PittFaculty of Science, Australian Institute for Microbiology and Infection, University of Technology Sydney, Ultimo, New South Wales, Australia.
Joyce ToFaculty of Science, Australian Institute for Microbiology and Infection, University of Technology Sydney, Ultimo, New South Wales, Australia.
Sarah ReedMass Sperectometry Facility, The University of Queensland Centre for Clinical Research (UQCCR), Medicine and Behavioural Sciences, The University of Queensland, St Lucia, Queensland, Australia.
Patrick N A HarrisFaculty of Health, The University of Queensland Centre for Clinical Research (UQCCR), Medicine and Behavioural Sciences, The University of Queensland, St Lucia, Queensland, Australia.ORCID https://orcid.org/0000-0002-2895-0345
Garry S A MyersFaculty of Science, Australian Institute for Microbiology and Infection, University of Technology Sydney, Ultimo, New South Wales, Australia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

While investigating colony morphology variation within clinical isolates of Burkholderia pseudomallei (Bp) isolated from a single clinical infection, we identified two distinct strains (based on their multi-locus sequence type) from Bp TSV292. Reports of simultaneous co-infection are un-common, with only two studies in Thailand documenting such cases: (1) 2 out of 133 cases, and (2) 13 out of 59 patients infected with two to three polyclonal Bp strains exhibiting different genotypes. Here, we present the first comprehensive multi-omics characterization of co-infecting Bpstrains isolated from a single infection at a hospital in Townsville, Australia, in 2018. This finding impacts the design of future diagnosis and treatment of Bp.

Indexed as

Burkholderia pseudomalleiMelioidosisCoinfectionFemaleGenotypeHumansMaleMiddle AgedMultilocus Sequence TypingPhylogenyQueensland

Identifiers

PMID41411338
PMCPMC12714287

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.