ReviewJournal of experimental botany2026
Cross-kingdom RNAi: a universal mechanism of inter-organismal communication with many unknowns.
Review in Journal of experimental botany, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Sprayable dsRNA for integrated crop defense: mechanisms, delivery strategies, and translational challenges.Molecular biology reports · 2026Review
- Cross-kingdom RNA interference in the dysbiosis-mediated network of vocal fold fibrosis: a pathogenic hypothesis and molecular intervention targets.Frontiers in immunology · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
Abstract
Cross-kingdom RNAi (ck-RNAi) is a biological process in which small RNA (sRNA) molecules are transferred between organisms belonging to different kingdoms to silence specific genes. Although numerous instances of reciprocal ck-RNAi have been documented in plants, demonstrating a modulation of the interaction between plants and their pathogens, pests, or symbiotic partners, the underlying molecular mechanisms remain largely elusive. In this review, we distinguish between naturally occurring and transgene-based cases of ck-RNAi, examine the diverse mechanisms governing the transfer of primary ck-RNAi signals from donor to recipient organisms, and explore the prerequisites for their amplification and systemic spread. Finally, we highlight key unresolved questions concerning the mechanistic basis of ck-RNAi and offer a perspective on its potential role in co-evolutionary dynamics.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.