ArticleJournal of the American Chemical Society2026
Dispersive Fluorine/Bromine Interactions as Key Selectivity Determinant: Asymmetric Cyclopropanations with 3,3,3-Trifluoro-2-diazopropionate Catalyzed by a Heterochiral-at-The-Metal Centers Dirhodium Paddlewheel Complex.
Article in Journal of the American Chemical Society, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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Who cites it
2 citing papers in PubMed.
- Rhodium(III)-Catalyzed Asymmetric Synthesis of Silanes and Cyclopropanes From Diazo Compounds Using Chiral α-Pinene-Derived Indenyl Ligands.Angewandte Chemie (International ed. in English) · 2026Article
- Nickel-Catalyzed Enantioselective Coupling Reactions of Fluorinated Sorbamides with Aldehydes AffordingJournal of the American Chemical Society · 2026Article
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5 authors.
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Abstract
Asymmetric cyclopropanation reactions of 3,3,3-trifluoro-2-diazopropionate have so far been largely beyond the scope of dirhodium catalysts. This significant gap in coverage is now closed with the aid of a new class of paddlewheel complex with "backbone chirality", in which an array of only three different achiral ligands (acetamidate, trifluoroacetate, calix[4]arene dicarboxylate) renders the two rhodium centers inequivalent and chiral-at-the-metal each. The -NH group of the acetamidate engages the ester carbonyl of the metal carbene intermediate into favorable interligand hydrogen bonding, which in turn controls the trajectory of the incoming olefinic reaction partner. In addition, a dispersive interaction between the -CF
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