Evidence map›Paper›PMID 41410861›Full record

ArticleJournal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing2026

The prevalence, distribution and ablation of non-pulmonary vein triggers in older patients with paroxysmal atrial fibrillation.

Song Wu, Zhenye Chen, Zhaomin Li, Xingxing Sun, Zhengxian Tao, Xianlun Li, Hongwu Chen, Minglong Chen

Abstract read
PubMed Publisher
In one paragraph

Article in Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Song WuChina-Japan Friendship Hospital (Institute of Clinical Medical Sciences), Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China.
Zhenye ChenDepartment of Cardiology, The First Affiliated Hospital of Nanjing Medical University, No.300, Guangzhou Road, Nanjing, 210029, China.
Zhaomin LiDepartment of Cardiology, The Second Affiliated Hospital of Guangxi Medical University, Guangxi, China.
Xingxing SunDepartment of Cardiology, The Second People's Hospital of Lianyungang, Affiliated to Kangda College of Nanjing Medical University, Lianyungang, China.
Zhengxian TaoDepartment of Cardiology, The First Affiliated Hospital of Nanjing Medical University, No.300, Guangzhou Road, Nanjing, 210029, China.
Xianlun LiChina-Japan Friendship Hospital (Institute of Clinical Medical Sciences), Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China.
Hongwu ChenDepartment of Cardiology, The First Affiliated Hospital of Nanjing Medical University, No.300, Guangzhou Road, Nanjing, 210029, China. chenhongwu@njmu.edu.cn.ORCID http://orcid.org/0000-0002-0006-2485
Minglong ChenDepartment of Cardiology, The First Affiliated Hospital of Nanjing Medical University, No.300, Guangzhou Road, Nanjing, 210029, China.

Funding

National Natural Science Foundation of China 82170322
6 · The paper itself

Abstract

objectivesTo investigate the prevalence, distribution and ablation of non-pulmonary vein (PV) triggers in older patients with paroxysmal atrial fibrillation (AF).

methodsA total of 694 patients aged 65-80 receiving index ablation for paroxysmal AF were included. These patients were divided as follows: patients without low-voltage areas (LVA) (n = 437), LVA patients with modification (n = 175), and LVA patients without modification (n = 82). Following propensity score matching (PSM) analysis, two sets of matched groups emerged: LVA patients without modification (Group A, n = 77) and patients without LVA (Group B, n = 77), and patients without LVA (Group C, n = 168) and LVA patients with modification (Group D, n = 168). The clinical endpoint was defined as the detection of ATA lasting longer than 30 s through ECG documentation or Holter recordings following the index ablation.

resultsFifty-seven (8.2%) patients were identified with non-PV triggers, mostly originating from superior vena cava (SVC). Compared with Group A, Group B exhibited a higher prevalence of non-PV triggers (18.2% vs. 6.5%, p = 0.027). Likewise, Group C showed a higher prevalence compared with Group D (14.3% vs 7.1%, p = 0.034). Over a mean follow-up of 19.7 months, there was no significant difference in ATA recurrence between patients with non-PV triggers ablation (n = 57) and without non-PV triggers (n = 637) (71.9% vs 74.9%, p = 0.458).

conclusionsAmong older patients with paroxysmal AF, non-PV triggers exhibit a lower prevalence, originate mostly from SVC, and present less frequently in patients with LVA.

Indexed as

Atrial FibrillationCatheter AblationAgedAged, 80 and overElectrocardiographyElectrocardiography, AmbulatoryFemaleHumansMalePrevalencePropensity ScorePulmonary VeinsRetrospective StudiesTreatment OutcomeVena Cava, SuperiorCatheter ablationLow-voltage areasNon-pulmonary vein triggersOlder patientsParoxysmal atrial fibrillation

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.