ArticleClinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis
Diagnostic Performance of Von Willebrand Activity Versus Ristocetin Cofactor Tests in the Primary Evaluation of Von Willebrand Disease in Colombia.
Article in Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
BackgroundAccurate diagnosis of Von Willebrand Disease (VWD) is essential for effective management, but no single test can definitively confirm it due to the disease's complexity and the limitations of current methods. Tests measuring Von Willebrand Factor (VWF) binding activity, such as the platelet-dependent VWF activity test (VWF:Ab), have been developed, but their application in Latin American populations remains underexplored. This study aimed to evaluate the performance of the VWF:Ab test compared to the Ristocetin Cofactor test (VWF:GPIbR) in a Colombian population with suspected or confirmed VWD.MethodsA diagnostic cross-sectional and retrospective study was conducted, including adults referred for hematological evaluation due to a personal or family history of bleeding disorders. Samples were analyzed using both VWF:GPIbR and VWF:Ab tests (HemosIL
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