ReviewJournal of agricultural and food chemistry2025
Natural Deep Eutectic Solvents (NADES) in Food Systems: Emerging Applications, Extraction Efficiency, Safety Concerns, and Regulatory Challenges.
Review in Journal of agricultural and food chemistry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
16 citing papers in PubMed.
- Towards Sustainable Recovery of Phenolics, Proteins, and Arabinoxylans from Brewer's Spent Grain Through Deep Eutectic Solvents: Extraction Strategies, Structure-Function Relationships, and Food Biorefinery Perspective.Foods (Basel, Switzerland) · 2026Review
- Antifungal Activity of Organic Acid-Based Natural Deep Eutectic Solvents against Necrotrophic PhytopathogenACS omega · 2026Article
- NADES-Extracted SunGold Kiwifruit Polyphenols as Functional Ingredients in Antioxidant-Enriched Yoghurt.Antioxidants (Basel, Switzerland) · 2026Article
- Deep eutectic solvent-based extraction and recovery of phenolic compounds: From conventional media to switchable recovery strategies.Mikrochimica acta · 2026Review
- From Oilseed Waste to High-Value Bioactives: Deep Eutectic Solvents as Sustainable Refining Media.International journal of molecular sciences · 2026Review
- Development and Characterization of Functional Gummies Enriched with País Grape Extract for Presbyphagia.Gels (Basel, Switzerland) · 2026Article
- Red Seaweed-Derived Phycobiliproteins: Marine Bioactive Colorants with Functional Health Properties.Marine drugs · 2026Review
- Ultrasound-Assisted NADES-Based Extraction of Spirulina Bioactives: Bioaccessibility and Intestinal Permeability Assessment Using an In Vitro Digestion/Caco-2 Cell Model and Food Application.Journal of food science · 2026Article
- Review
- Advanced Green Extraction Methods for Valorising Artichoke Waste: Bioactive Composition, Stabilisation, and Implications for Nutrition and Disease Prevention.Foods (Basel, Switzerland) · 2026Review
- Upcycling Black Garlic Peels into Multifunctional Cosmeceutical Extracts: Antioxidants and UV-Shielding via Antimicrobial Natural Deep Eutectic Solvents.Antioxidants (Basel, Switzerland) · 2026Article
- Sustainable Valorization of Avocado By-Products: Green Extraction of Phenolics with NaDES and Their Use in Fresh-Cut Fruit Preservation.Foods (Basel, Switzerland) · 2026Article
- Recent Advances in NADES-Assisted Process Intensification Technologies for Sustainable Recovery of Microalgal Bioactives: Challenges and Future Prospectives.Marine drugs · 2026Review
- Unlocking the Potential of Natural Deep Eutectic Solvents for the Valorization of Different Biological Materials.Molecules (Basel, Switzerland) · 2026Article
- Deep eutectic solvent extraction of lotus peel proanthocyanidins and its anti-senescence mechanism in t-BHP induced HepG2 cells.Frontiers in nutrition · 2026Article
- Structural characterization and Pickering emulsifying ability of Tartary buckwheat starch prepared by natural deep eutectic solvent method.Frontiers in nutrition · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
11 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Natural deep eutectic solvents (NADES) have emerged as green alternatives to conventional organic solvents in food processing. They are biodegradable, nonvolatile, and highly efficient at solubilizing bioactive molecules, including polyphenols, flavonoids, anthocyanins, carotenoids, and alkaloids. From 2020 to 2025, significant advances have clarified their composition, physicochemical behavior, interaction mechanisms, and technological uses in foods. Rational combinations of hydrogen-bond donors and acceptors, often composed of substances classified as Generally Recognized as Safe (GRAS), enable selective and high-yield extraction from plants, agro-industrial byproducts, and food waste. Coupling NADES with ultrasound, microwave, or pressurized extraction has increased efficiency while protecting heat-sensitive compounds. Beyond extraction, NADES show promise as preservatives, delivery systems, encapsulating media, color stabilizers, and natural antioxidants in meat, dairy, fermented, and plant-based products. Remaining bottlenecks include high viscosity, scarce toxicological and metabolic data, absence of specific regulations, and limited research on sensory impacts and shelf life under realistic large-scale industrial conditions.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.