Evidence map›Paper›PMID 41410551›Full record

ArticleEuropean journal of physical and rehabilitation medicine2025

Assessment of gait patterns in breast cancer survivors: a cross-sectional study.

Chiara Notarstefano, Valentina Azzollini, Mirella Ferrari, Simone Carozzo, Stefania Dalise, Matteo Ghilli, Manuela Roncella, Carmelo Chisari

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Article in European journal of physical and rehabilitation medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

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1citing papers in PubMed
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1 · What the graph read from it

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3 · Its place in the literature

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1 citing paper in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

8 authors.

Chiara NotarstefanoDepartment of Translational Research and New Technologies in Medicine and Surgery, University of Pisa, Pisa, Italy.
Valentina AzzolliniDepartment of Translational Research and New Technologies in Medicine and Surgery, University of Pisa, Pisa, Italy - valentina.azzollini@unipi.it.
Mirella FerrariUnit of Neurorehabilitation, University Hospital of Pisa, Pisa, Italy.
Simone CarozzoS. Anna Institute, Crotone, Italy.
Stefania DaliseUnit of Neurorehabilitation, University Hospital of Pisa, Pisa, Italy.
Matteo GhilliBreast Cancer Centre, University Hospital of Pisa, Pisa, Italy.
Manuela RoncellaBreast Cancer Centre, University Hospital of Pisa, Pisa, Italy.
Carmelo ChisariDepartment of Translational Research and New Technologies in Medicine and Surgery, University of Pisa, Pisa, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundBreast Cancer Survivors (BCs) often exhibit impaired mobility, balance deficits, and reduced gait speed at functional tests.

aimTo assess gait patterns in a population of BCs by comparing spatiotemporal (ST) gait measures with those of healthy subjects.

designCross-sectional study.

settingOutpatient rehabilitation services of the Breast Unit and the Motion Analysis Laboratory at the Neurorehabilitation Unit, University Hospital of Pisa, Italy. POPULATION: Twenty-three BCs (BCs-group), who completed active oncological treatments at least 3 months prior to study enrolment, and 16 age-matched healthy female controls (HC).

methodsAll subjects underwent 3-D gait analysis. ST measures of gait were compared between BCs-group and HC. Intra-patient comparisons were made between the operated and the contralateral side. BCs-group was then stratified into two sub-groups according to time from surgery (<12 months; >12 months) and compared to HC.

resultsResults obtained provide evidence that BCs display an abnormal gait pattern characterized by slower gait velocity (0.66±0.21 vs. 0.89±0.22 m/s, P<0.01), shorter step length (0.48±0.10 vs. 0.54±0.07 m; P<0.05) and stride length (0.90±0.16 vs. 1.07±0.14 m; P<0.01), and increased step width (0.12±0.03 vs. 0.10±0.03 m; P<0.01). Cadence was also reduced (81.12±13.68 vs. 98.78±12.48 steps/min; P<0.01) while time of stance (63.1±3.7 vs. 57.69±3.69%; P<0.01) and double support time (14.53±4.85 vs. 8.39±2.87%; P<0.01) were significantly prolonged. The intrapatient analysis of ST measures between the operated and unoperated side revealed no significant differences, but abnormal step length and step width were found only on the operated side. Altered ST parameters were already detectable within 12 months from breast surgery.

conclusionsA slower and less stable gait pattern develops early after BC treatments, and it can be detected by assessment of ST measures within 12 months from breast surgery. CLINICAL REHABILITATION IMPACT: Early tailored rehabilitation may help prevent gait deterioration and reduce fall risk in BCs.

Indexed as

Breast NeoplasmsCancer SurvivorsGaitGait Disorders, NeurologicAdultAgedCase-Control StudiesCross-Sectional StudiesFemaleGait AnalysisHumansMiddle AgedPostural Balance

Identifiers

PMID41410551
PMCPMC12952240

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.