Evidence map›Paper›PMID 41410209›Full record

ReviewMicrobial biotechnology2025

Subsurface Life on Earth as a Key to Unlock Extraterrestrial Mysteries.

Emeline Vidal, Melody R Lindsay, James A Bradley, Magdalena R Osburn, S Emil Ruff

Abstract readReview
In one paragraph

Review in Microbial biotechnology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Emeline VidalMarine Biological Laboratory, Ecosystems Center and J Bay Paul Center for Comparative Molecular Biology and Evolution, Woods Hole, Massachusetts, USA.ORCID 0009-0009-4637-9435
Melody R LindsayBigelow Laboratory for Ocean Sciences, East Boothbay, Maine, USA.
James A BradleyAix Marseille Université, Université de Toulon, CNRS, IRD, MIO, Marseille, France.
Magdalena R OsburnDepartment of Earth, Environmental, and Planetary Sciences, Northwestern University, Evanston, Illinois, USA.
S Emil RuffMarine Biological Laboratory, Ecosystems Center and J Bay Paul Center for Comparative Molecular Biology and Evolution, Woods Hole, Massachusetts, USA.ORCID 0000-0002-6872-6188

Funding

Agence Nationale de la Recherche ANR23-CPJ1-0172-01CIFAR Earth 4DDavid and Lucile Packard FoundationEuropean Research Council 101115755Human Frontier Science Program https://doi.org/10.52044/HFSP.RGEC342023.pc.gr.168586Human Frontier Science Program https://doi.org/10.52044/HFSP.RGY00582022.pc.gr.153592NASA Exobiology 80NSSC23K1355National Science Foundation EAR-2042249National Science Foundation EAR-2120912National Science Foundation OCE-1450528United States Science Support Program
6 · The paper itself

Abstract

The first forms of life on Earth were microbial, preceding the evolution of multicellular life by more than two billion years. Based on our current understanding of the origin of life, it is likely that the first life forms on any extraterrestrial world would also be microbial. Due to the extreme temperatures, radiation or aridity on most planetary surfaces, such extraterrestrial microbes would most likely dwell in subsurface environments. Earth's subsurface features a wide range of environments, including deep marine sediments, crustal aquifers, rock fracture fluids, hydrocarbon reservoirs, caves and permafrost soils. These environments are known to host an immense diversity of life forms, predominantly microbes that survive or even thrive under extreme conditions and energy scarcity. Life's ability to endure and possibly evolve in Earth's subsurface lends credence to the possible existence of life beyond our planet and provides a blueprint for the extraterrestrial life forms and biosignatures we might expect. The exploration of space via extraterrestrial samples analysed on Earth, in situ extraterrestrial analyses, and remote sensing continue to advance our search for and understanding of potential biosignatures on other planetary bodies. But by investigating Earth's deep, dark and isolated ecosystems, we not only broaden our understanding of life's adaptability but also refine our strategies and technologies for detecting life on other planets and moons. Subsurface exploration is not just a frontier of Earth science-it is a cornerstone of astrobiology and in the pursuit of understanding the multitude of processes that could create and sustain life anywhere. In this opinion article, we discuss the latest highlights in subsurface research and technology, how Earth's subsurface environments serve as models for potential environments on other planetary bodies, why insights into subsurface microbiomes inform the search for life elsewhere, and which technologies and developments will advance the field in the future.

Indexed as

ExobiologyExtraterrestrial EnvironmentGeologic SedimentsMicrobiotaOrigin of LifeEarth, Planetastrobiologydeep biosphereextremophilesmicrobial ecologyscientific drilling

Identifiers

PMID41410209
PMCPMC12712870

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.