Evidence map›Paper›PMID 41409966›Full record

ArticleCureus2025

Evaluation of Antimicrobial Efficacy of Arjuna, Bromelain, Calcium Hydroxide, and Triple Antibiotic Paste as an Intracanal Medicament Against Enterococcus faecalis: An In Vitro Study.

Ranjana H Deshmukh, Neelam Chandwani, Anjali Gayke, Neeta Gade, Reetika Reetika, Manish Shrigiriwar

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Ranjana H DeshmukhConservative Dentistry and Endodontics, All India Institute of Medical Sciences, Nagpur, Nagpur, IND.
Neelam ChandwaniDentistry, All India Institute of Medical Sciences, Nagpur, Nagpur, IND.
Anjali GaykeConservative Dentistry and Endodontics, All India Institute of Medical Sciences, Nagpur, Nagpur, IND.
Neeta GadeMicrobiology, All India Institute of Medical Sciences, Nagpur, Nagpur, IND.
Reetika ReetikaConservative Dentistry and Endodontics, All India Institute of Medical Sciences, Nagpur, Nagpur, IND.
Manish ShrigiriwarForensic Medicine, All India Institute of Medical Sciences, Nagpur, Nagpur, IND.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introduction

aimThis study aimed to evaluate and compare the antimicrobial efficacy of two novel herbal agents,

methodsEighty human teeth with single roots were endodontically prepared and divided into five groups: Group 1 (Arjuna paste), Group 2 (CaOH), Group 3 (TAP), Group 4 (bromelain paste), and Group 5 as a control with no medicament. After bacterial inoculation and a three-week incubation period, canals were instrumented and irrigated. Antimicrobial efficacy was assessed by measuring the reduction in bacterial colony-forming units (CFUs) after seven days of intracanal medicament application.  Results: The highest percentage of bacterial reduction was seen in TAP (99.89%), followed by bromelain paste (98.57%) and Arjuna paste (99.02%). CaOH showed the lowest reduction (93.27%) in bacterial load.

conclusionThe results suggest that while TAP remains a highly effective intracanal medicament against

Indexed as

anti-bacterial agentsantimicrobial efficacybromelaincalcium hydroxideendodonticsenterococcus faecalisterminalia arjunatriple antibiotic paste

Identifiers

PMID41409966
PMCPMC12707169

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.