Evidence map›Paper›PMID 41409920›Full record

ArticleCureus2025

Lemmel Syndrome Without Choledocholithiasis as a Cause of Recurrent Hepatocellular Injury: A Case Report.

Kyoko Hanaoka, Shingo Shimada, Yoichi Miyaoka, Yuya Kanemitsu, Nobuhiko Abe

Abstract readCase Reports
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Kyoko HanaokaInternal Medicine, Abashiri-Kosei General Hospital, Abashiri, JPN.
Shingo ShimadaSurgery, Otaru General Hospital, Otaru, JPN.
Yoichi MiyaokaGeneral Surgery, Abashiri-Kosei General Hospital, Abashiri, JPN.
Yuya KanemitsuInternal Medicine, Abashiri-Kosei General Hospital, Abashiri, JPN.
Nobuhiko AbeInternal Medicine, Abashiri-Kosei General Hospital, Abashiri, JPN.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Lemmel syndrome is a rare cause of stone-negative biliary obstruction due to external compression of the distal common bile duct by a periampullary duodenal diverticulum (PAD). We report a 67-year-old man with recurrent episodes of liver dysfunction due to Lemmel syndrome. On admission, laboratory tests showed marked hepatocellular injury with cholestasis. Contrast-enhanced CT demonstrated a PAD abutting and compressing the distal bile duct with upstream dilatation, without choledocholithiasis. Endoscopic retrograde cholangiopancreatography (ERCP) with sphincterotomy and balloon sweeping yielded sludge-like bile, after which liver tests rapidly improved. This case underscores the need to consider PAD-related transient obstruction in stone-negative, recurrent hepatocellular flares and highlights the diagnostic-therapeutic value of timely endoscopic biliary decompression.

Indexed as

endoscopic retrograde cholangiopancreatography (ercp)ercplemmel syndromeobstructive jaundiceperiampullary duodenal diverticulatransaminitis

Identifiers

PMID41409920
PMCPMC12705858

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.