Evidence map›Paper›PMID 41409869›Full record

ArticleSurgical neurology international2025

Improving glioma resection with 2D-intraoperative ultrasound: Observational results and systematic literature correlation.

Octavian Mihai Sirbu, Alin Vasile Chirtes, Lucian George Eftimie, Andreea Plesa, Marian Mitrica, Mircea Radu Gorgan

Abstract read
In one paragraph

Article in Surgical neurology international, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Octavian Mihai SirbuDepartment of Neurosurgery, University of Medicine and Pharmacy "Carol Davila," Bucharest, Romania.
Alin Vasile ChirtesDepartment of Neurosurgery, Central Military Emergency University "Dr. Carol Davila" Hospital, Bucharest, Romania.
Lucian George EftimieDepartment of Pathology, Central Military Emergency University "Dr. Carol Davila" Hospital, Bucharest, Romania.
Andreea PlesaDepartment of Neurology, Central Military Emergency University "Dr. Carol Davila" Hospital, Bucharest, Romania.
Marian MitricaDepartment of Neurosurgery, Central Military Emergency University "Dr. Carol Davila" Hospital, Bucharest, Romania.
Mircea Radu GorganDepartment of Neurosurgery, University of Medicine and Pharmacy "Carol Davila," Bucharest, Romania.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Maximizing tumor resection is a key prognostic factor in glioma surgery. Intraoperative cerebral ultrasonography (IOUS) offers real-time, cost-effective guidance that can enhance the extent of resection (EOR) and gross total resection (GTR) rates, but data remain heterogeneous. Methods: We conducted a retrospective analysis of a prospective observational database including patients with gliomas undergoing surgery with or without IOUS guidance in one tertiary neurosurgical center. Inclusion criteria were preoperative magnetic resonance imaging-suspected gliomas, intended GTR, and available early postoperative imaging. Outcomes were compared using propensity score matching. In addition, a systematic literature review covering 2018-2024 was performed following Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines. Results: A total of 38 patients were included after matching, with 19 patients in each group. IOUS use significantly improved the mean EOR (85.0% vs. 66.2%, Conclusion: IOUS significantly enhances resection outcomes in glioma surgery and demonstrates a progressive benefit with surgeon experience. Given its versatility, low cost, and growing integration with technologies such as contrast-enhanced ultrasound and artificial intelligence, IOUS remains a fundamental tool in modern neurooncology. Future multicenter prospective studies are needed to standardize its use and assess long-term patient outcomes.

Indexed as

Extent of resectionGlioblastomaGliomaImaging-guided resectionIntraoperative cerebral ultrasound

Identifiers

PMID41409869
PMCPMC12707705

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.