ArticleSurgical neurology international2025
A case of rapidly progressive cervical primary spinal epidural lymphoma.
Article in Surgical neurology international, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Background: Primary spinal epidural lymphoma (PSEL) is rare, accounting for just 0.1-6.5% of all extranodal lymphomas and 9% of all primary spinal epidural tumors. They are mostly located in the thoracic spine, with only occasional cervical spine involvement. Here, a 74-year-old male presented with a cervical epidural diffuse large B-cell lymphoma (DLBCL) that was successfully managed with an emergent surgical decompression. Case Description: A 74-year-old male presented with the acute onset of quadriparesis. The magnetic resonance imaging (MRI) revealed thickening of the posterior longitudinal ligament at C2-3, an epidural mass posterior to the spinal cord from C3-5, causing spinal cord compression, maximal at the C4-5 level. Six days after admission, the patient underwent a C2 partial and full C3-4 laminectomy; it resulted in improvement of quadriparesis. Pathology confirmed the diagnosis of CD20-positive DLBCL, and he subsequently received appropriate chemotherapy/radiotherapy. Conclusion: Spinal cord compression is the sole presenting symptom in <5% of malignant lymphoma cases. Here, a 74-year-old male developed an acute quadriparesis attributed to a C3-C5 DLBCL that was successfully managed with a C2-C4 laminectomy, followed by appropriate chemotherapy and radiation.
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