ArticleSurgical neurology international2025
Anatomical considerations in acromegalic patients: A multicentric cohort study.
Article in Surgical neurology international, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
13 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Changes in craniofacial morphology due to elevated levels of growth hormone (GH) vary according to ethnic groups studied in the international literature. We aimed to evaluate the radiologic and endoscopic anatomical variations in acromegalic patients, in comparison with non-functioning pituitary adenomas (NFPA) in the Mexican population. Methods: One hundred and fifteen patients with endocrinologically and histologically confirmed diagnosis of GH-secreting pituitary adenoma (PA) and NFPA, treated only by endoscopic endonasal approach, in ten different institutions in Mexico, were studied over a 1-year period. Hormonal levels of GH, somatomedin, preoperative neuroimaging, and intraoperative endoscopy were analyzed to evaluate morphological changes specific to the Mexican population. Results: A higher number of GH-producing macroadenomas was obtained for this study (69.2%), which was directly related to the hypertrophy of the turbinate mucosa in 63.5% ( Conclusion: Mexican acromegalic patients present subtle morphological changes that can affect the safety and efficacy of the endonasal approach, primarily in the nasal and sphenoid phases.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.