Evidence map›Paper›PMID 41409796›Full record

ArticleInternational journal of preventive medicine2025

Two GWAS Suggestive-SNVs in the Zinc Transporter 8 Gene Synergistically Influence Insulin Resistance in Type 2 Diabetes.

Abdolkarim Mahrooz, Mina Safari, Mani Nosrati, Mehran Ahmadi, Ahad Alizadeh

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of preventive medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Abdolkarim MahroozImmunogenetics Research Center, Department of Clinical Biochemistry and Medical Genetics, Mazandaran University of Medical Sciences, Sari, Iran.
Mina Safari *Department of Clinical Biochemistry and Medical Genetics, Faculty of Medicine, Mazandaran University of Medical Sciences, Sari, Iran.
Mani Nosrati *Department of Clinical Biochemistry and Medical Genetics, Faculty of Medicine, Mazandaran University of Medical Sciences, Sari, Iran.
Mehran AhmadiDepartment of Biochemistry, Science and Research Branch, Islamic Azad University, Tehran, Iran.
Ahad AlizadehMedical Microbiology Research Center, Department of Epidemiology and Biostatistics, Qazvin University of Medical Sciences, Qazvin, Iran.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: According to the genome-wide association studies (GWASs), zinc transporter 8 ( Methods: A total of 261 subjects were included in this study. Insulin and fasting glucose concentrations were used to calculate the homeostasis model assessment for insulin resistance (HOMA-IR) index. The study variants were genotyped by polymerase chain reaction (PCR)-based restriction analysis. Results: For both variants, the HOMA-IR index is enhanced in the order of risk allele-carrying genotypes (GG<GA<AA for Conclusions: In addition to individual effects on

Indexed as

Diabetes mellitusgenetic variationinsulin resistancetype 2zinc transporter 8

Identifiers

PMID41409796
PMCPMC12707829

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.