Evidence map›Paper›PMID 41409726›Full record

ReviewRSC advances2025

Application of MOFs-mediated phototherapy in cancer treatment.

Mengyu Xu, Liyuan Wang, Yuanxin Chen, Lihua Ma, Min Liu, Long Wang, Jing Huan, Lijuan Wang, Yanxi Zhu

Abstract readReview
In one paragraph

Review in RSC advances, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Mengyu XuCentral Laboratory, Linyi People's Hospital, School of Clinical Medicine, Shandong Second Medical University Shandong China wanglj730@163.com zhu-yanxi@163.com.
Liyuan WangPostgraduate Training Base of Linyi People's Hospital, Guangzhou University of Chinese Medicine Linyi China.
Yuanxin ChenCentral Laboratory, Linyi People's Hospital, School of Clinical Medicine, Shandong Second Medical University Shandong China wanglj730@163.com zhu-yanxi@163.com.
Lihua MaCentral Laboratory, Linyi People's Hospital, School of Clinical Medicine, Shandong Second Medical University Shandong China wanglj730@163.com zhu-yanxi@163.com.
Min LiuCentral Laboratory, Linyi People's Hospital, School of Clinical Medicine, Shandong Second Medical University Shandong China wanglj730@163.com zhu-yanxi@163.com.
Long WangCentral Laboratory, Linyi People's Hospital, School of Clinical Medicine, Shandong Second Medical University Shandong China wanglj730@163.com zhu-yanxi@163.com.
Jing HuanDepartment of Traditional Chinese Medicine, Linyi People's Hospital Linyi Shandong 276000 China 562625718@qq.com.
Lijuan WangCentral Laboratory, Linyi People's Hospital, School of Clinical Medicine, Shandong Second Medical University Shandong China wanglj730@163.com zhu-yanxi@163.com.
Yanxi ZhuCentral Laboratory, Linyi People's Hospital, School of Clinical Medicine, Shandong Second Medical University Shandong China wanglj730@163.com zhu-yanxi@163.com.ORCID https://orcid.org/0000-0002-7172-4087

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This article systematically discusses the latest progress of metal-organic frameworks (MOFs) in the field of cancer phototherapy. MOFs have overcome the limitations of conventional materials in structural design and functional tunability, offering ultra-high specific surface area, high porosity, and customizable active sites, which render them highly suitable as nanocarriers. In photodynamic therapy (PDT), MOFs can significantly improve the efficiency of ROS generation by loading photosensitizers or directly as photosensitive materials, and enhance tumour specificity by targeted modifications. In the field of photothermal therapy (PTT), MOFs have shown excellent near-infrared light absorption and conversion ability by integrating precious metal nanoparticles or designing novel ligand systems. It is worth noting that MOFs-mediated multimodal treatment strategies are increasingly mature. These innovations provide an important theoretical basis and technical path for the development of high-efficiency and low-toxicity nano-phototherapy systems.

Identifiers

PMID41409726
PMCPMC12706733

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.