In one paragraphArticle in medRxiv : the preprint server for health sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from itWhat it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registryThe trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
3 · Its place in the literatureWho cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
4 · The recordCorrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what moneyAuthors and funding
25 authors.
Mariela V JenningsDepartment of Psychiatry, University of California San Diego, La Jolla CA, USA.
Aisha SallahGenetics and Epigenetics Graduate Group, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.ORCID 0009-0009-1199-6900 Zeal JinwalaDepartment of Psychiatry, University of Pennsylvania, Philadelphia, PA 19104, United States.ORCID 0009-0005-5062-0827 Hayley Ha ThorpeDepartment of Anatomy and Cell Biology, Schulich School of Medicine and Dentistry, Western University, London, ON, Canada.ORCID 0000-0002-7263-637X John MeredithDepartment of Psychiatry, University of California San Diego, La Jolla CA, USA.
Kyra FeuerDepartment of Psychiatry, University of Pennsylvania, Philadelphia, PA 19104, United States.ORCID 0000-0003-3704-6136 Natasia Courchesne-KrakDepartment of Psychiatry, University of California San Diego, La Jolla CA, USA.ORCID 0000-0002-9231-647X Maria NiarchouDepartment of Medicine, Division of Genetic Medicine, Vanderbilt University Medical Center, Nashville, TN, USA.ORCID 0000-0002-8855-7393 23andMe Research Team
Lea K DavisDepartment of Biomedical Informatics, Vanderbilt University Medical Center, Nashville, TN, USA.ORCID 0000-0001-5143-2282 Alexander S HatoumWashington University School of Medicine, Department of Psychiatry, St. Louis MO.
Travis T MallardCenter for Precision Psychiatry, Department of Psychiatry, Massachusetts General Hospital, Boston, MA, USA.ORCID 0000-0002-3265-3001 Jeanne E SavageDepartment of Complex Trait Genetics, Center for Neurogenomics and Cognitive Research, Vrije Universiteit Amsterdam, Amsterdam Neuroscience, Amsterdam, The Netherlands.ORCID 0000-0002-2034-8341 Rachel L KemberDepartment of Psychiatry, University of Pennsylvania, Philadelphia, PA 19104, United States.ORCID 0000-0001-8820-2659 Funding
Phenotypic Diversity in COVID-19UL1TR001878 · NCATS · UNIVERSITY OF PENNSYLVANIA · PI FITZGERALD, GARRET A · 2016 to 2025
$102.4MInterdisciplinary Research Fellowship in NeuroAIDSR25MH081482 · NIMH · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI MARIANA CHERNER · 2007 to 2026
$5.2M2/7 PsycheMERGE: Advancing Precision PsychiatryR01MH137218 · NIMH · MASSACHUSETTS GENERAL HOSPITAL · PI JORDAN W SMOLLER · 2024 to 2026
$2.4MBuilding Bridges to Allow Cross-species Translational genetics for the Study of AddictionDP1DA054394 · NIDA · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI SANCHEZ ROIGE, SANDRA · 2021 to 2025
$2.4MGraduate Training Program in BioinformaticsT32GM139790 · NIGMS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI BAFNA, VINEET, GAASTERLAND, THERESA · 2021 to 2025
$2.1M1/7-PsycheMERGE: Advancing Precision PsychiatryR01MH137220 · NIMH · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI Lea K Davis · 2024 to 2026
$1.8M4/7-PsycheMERGE: Advancing Precision PsychiatryR01MH137212 · NIMH · UNIVERSITY OF PENNSYLVANIA · PI Rachel Lorraine Kember · 2024 to 2026
$1.5MIdentifying genetic sources of comorbidity between cannabis and schizophrenia using genome-wide and integrative omics dataK01DA051759 · NIDA · WASHINGTON UNIVERSITY · PI JOHNSON, EMMA COVEY · 2021 to 2025
$816kNCATS NIH HHS UL1 TR001878NIDA NIH HHS DP1 DA054394NIDA NIH HHS K01 DA051759NIGMS NIH HHS T32 GM139790NIMH NIH HHS R01 MH137212NIMH NIH HHS R01 MH137218NIMH NIH HHS R01 MH137220NIMH NIH HHS R25 MH081482
6 · The paper itselfAbstract
Sex differences in alcohol use behaviors are well-established: males typically engage in heavier and more frequent drinking and exhibit more externalizing behaviors (e.g., other substance use), while females often transition to dependence more rapidly and present more internalizing psychopathology (e.g., depression). The biological mechanisms underpinning these differences are relatively unknown. In this study, we investigated the sex-differentiated genetic architecture of 11 alcohol use phenotypes pertaining to frequency, quantity and problematic use by leveraging sex-stratified genome-wide association studies (Ns 40,335 to 613,148). Specifically, we compared SNP-based heritability (
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PMID41409681
PMCPMC12706599
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