Evidence map›Paper›PMID 41409677›Full record

ArticlemedRxiv : the preprint server for health sciences2025

The Progressive Aphasia Communication Toolkit (PACT): A Strengths-Based Approach to Multidomain Evaluation for Intervention.

Jeanne Gallée, Jade Cartwright, Maya L Henry, Aimee R Mooney, Brielle C Stark, Anna Volkmer, Aimee Dietz, Connie Nakano, Petronilla Battista, Ashleigh Beales and 27 more

Abstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in medRxiv : the preprint server for health sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

37 authors.

Jeanne GalléeDepartment of Medicine, University of Washington, Seattle.ORCID 0000-0002-9338-2727
Jade CartwrightSchool of Health Sciences, University of Tasmania, Hobart, Australia.ORCID 0000-0002-6381-6184
Maya L HenryDepartment of Speech, Language, and Hearing Sciences, University of Texas-Austin, Austin, TX, United States of America.
Aimee R MooneyDepartment of Neurology, Oregon Health & Science University, Portland, OR, United States of America.ORCID 0000-0002-3642-8995
Brielle C StarkDepartment of Speech, Language, and Hearing Sciences, Indiana University, Bloomington, IN, United States of America.
Anna VolkmerDivision of Psychology and Language Sciences, University College London, London, UK.
Aimee DietzDepartment of Communication Sciences and Disorders, University of South Florida, Tampa, FL, USA.
Connie NakanoDepartment of Medicine, University of Washington, Seattle.
Petronilla BattistaIstituti Clinici Scientifici Maugeri IRCCS, Laboratory of Neuropsychology, Institute of Bari, Bari, Italy.
Ashleigh BealesSpeech Rehab Centre, Perth, Australia.
Bárbara Costa BeberDepartment of Speech, Language and Hearing Sciences, Universidade Federal de Ciências da Saúde de Porto Alegre (UFCSPA), Porto Alegre, Rio Grande do Sul, Brazil.
Inês CadórioRISE-Health, Escola Superior de Saúde Fernando Pessoa, Fundação Ensino e Cultura Fernando Pessoa, Porto, Portugal.
Megan CaldwellDepartment of Speech and Hearing Sciences, University of Washington, Seattle, WA, USA.
Katharine DaviesSchool of Audiology and Speech Sciences, The University of British Columbia, Vancouver, Canada.
Zoe EzzesSchool of Speech, Language, and Hearing Sciences, San Diego State University, San Diego, CA, USA.
Mirjam GauchDepartment of Psychiatry and Psychotherapy, University Medical Center of the Johannes Gutenberg University Mainz, 55131 Mainz, Germany.
Tracey GraneyTracey Graney Speech Pathology, Hobart, Tasmania, Australia.
Simon GroblerNational Hospital for Neurology and Neurosurgery, London, UK.
Katarina L HaleyDivision of Speech and Hearing Sciences, Department of Health Sciences, School of Medicine, University of North Carolina, Chapel Hill, NC, USA.
Alessa HausmannDepartment of Psychology, University of Geneva, Geneva, Switzerland.
Elena HerreraDepartment of Psychology, University of Oviedo, Oviedo, Spain.
Honey I HubbardDepartment of Speech and Hearing Sciences, University of New Mexico, Albuquerque, NM, USA.
Regina JokelRotman Research Institute, Baycrest Academy for Research and Education, Toronto, Canada.
Leslie KotDepartment of Speech and Hearing Sciences, University of Washington, Seattle, WA, USA.
Mara LoweDepartment of Linguistics and Communication Disorders, CUNY Queens College, New York, NY, USA.
Ellen McGowanPennine Care NHS Foundation Trust, Manchester, UK.
Lotte MeteyardClinical Language Sciences, University of Reading, UK.
Núria MontagutAlzheimer's Disease and other Cognitive Disorders Unit. Hospital Clínic de Barcelona, Barcelona, Spain.
Iris NowensteinDepartment of Icelandic, University of Iceland, Reykjavík, Iceland.
Margaret PozzebonAge Right Speech Pathology, Melbourne, Australia.
Richard TalbotDivision of Psychology and Language Sciences, University College London, London, UK.
Cathy Taylor-RubinTaylor-Rubin Speech Language Pathology, Sydney, Australia.
Ffion WalkerHealthAbility, Melbourne, Australia.
Ingvild Elisabeth WinsnesDepartment of Linguistics and Scandinavian Studies, University of Oslo, Oslo, Norway.
Rob J FredericksenDepartment of Allergy and Infectious Diseases, University of Washington, Seattle, WA, USA.
Kimiko Domoto-ReillyAlzheimer's Disease Research Center, University of Washington, Seattle.
Paul K CraneDepartment of Medicine, University of Washington, Seattle.

Funding

MVP Data Integration into the ADSP Phenotype Harmonization ConsortiumU24AG074855 · NIA · VANDERBILT UNIVERSITY MEDICAL CENTER · PI CUCCARO, MICHAEL L, HOHMAN, TIMOTHY J · 2021 to 2025
$37.5M
University of Washington Alzheimer's Disease Research CenterP30AG066509 · NIA · UNIVERSITY OF WASHINGTON · PI Thomas J. Grabowski · 2020 to 2026
$29.0M
NIA NIH HHS P30 AG066509NIA NIH HHS U24 AG074855
6 · The paper itself

Abstract

introductionTools to document communicative ability in people living with primary progressive aphasia (PwPPA) are limited. This work describes the development of a strengths-based and ecologically-valid instrument-the

methodsThis work consisted of five experiments: two to develop (Experiments 1 and 2) and three to pilot (Experiments 3-5) a novel instrument for PPA. Ninety-five individuals worldwide contributed to this work: 80 researchers and clinicians, 9 PwPPA, and 6 care partners.

resultsExperiments 1-2 culminated in an instrument comprising four scales that capture quantitative and qualitative feedback. Experiments 3-5 resulted in structural refinement and digitization of the tool, revealed PwPPA and care partner preference for the PACT over traditional neuropsychological evaluation, and demonstrated strong inter-rater agreement for general measurability (91%) and strength ratings (85%). DISCUSSION: Current findings indicate that the PACT provides a holistic profile of communication strengths for PwPPA and can guide clinicians in developing functional therapeutic targets.

Indexed as

person-centered careprimary progressive aphasiaspeech-language pathologystrengths-based approachtherapeutic assessment

Identifiers

PMID41409677
PMCPMC12706597

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.