Evidence map›Paper›PMID 41409639›Full record

ArticleCurrent epidemiology reports2025

Consideration of Cardiovascular Morbidities in the Relationship between Ambient Air Pollution Exposure and Individual-Level Adverse COVID-19 Outcomes: A Systematic Review.

Sneha Kannoth, Kavitha Ganesan, Brandi Vollmer, Pam Factor-Litvak, Stephen S Morse, Earle C Chambers, Kristen M Rappazzo, Stephanie Lovinsky-Desir, Jeanette A Stingone

Abstract read
In one paragraph

Article in Current epidemiology reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Sneha KannothDepartment of Environmental Medicine, Icahn School of Medicine at Mount Sinai, 17 E. 102nd Street CAM Building, 3 West One Gustave L. Levy Place, New York, NY 10029, USA.
Kavitha GanesanMailman School of Public Health, Columbia University, New York, NY, USA.
Brandi VollmerMailman School of Public Health, Columbia University, New York, NY, USA.
Pam Factor-LitvakMailman School of Public Health, Columbia University, New York, NY, USA.
Stephen S MorseMailman School of Public Health, Columbia University, New York, NY, USA.
Earle C ChambersDepartment of Family and Social Medicine, Albert Einstein College of Medicine, Bronx, NY, USA.
Kristen M RappazzoOffice of Research and Development, Environmental Protection Agency, RTP, NC, USA.
Stephanie Lovinsky-DesirMailman School of Public Health, Columbia University, New York, NY, USA.
Jeanette A StingoneMailman School of Public Health, Columbia University, New York, NY, USA.

Funding

True Metal fac coreP30ES009089 · NIEHS · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI MATTHEW S PERZANOWSKI · 1998 to 2026
$44.7M
New York Regional Center for Diabetes Translation Research - Translational Intervention Methodology CoreP30DK111022 · NIDDK · ALBERT EINSTEIN COLLEGE OF MEDICINE, INC · PI JEFFREY GONZALEZ · 2016 to 2026
$7.8M
Research Training Program in Pediatric ExposomicsT32HD049311 · NICHD · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI KECIA Nicole CARROLL, Robert O Wright · 2007 to 2026
$7.4M
Global HIV Implementation Science Research Training Grant RenewalT32AI114398 · NIAID · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI Yael R Hirsch-Moverman · 2014 to 2026
$4.1M
A DATA SCIENCE APPROACH TO AIR TOXICS AND CHILDREN'S ENVIRONMENTAL HEALTHR00ES027022 · NIEHS · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI STINGONE, JEANETTE A · 2018 to 2020
$742k
Physical Activity and Dose of Air Pollution in Pediatric Urban Asthma: Impact of Minute VentilationK01HL140216 · NHLBI · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI LOVINSKY-DESIR, STEPHANIE · 2018 to 2021
$692k
NHLBI NIH HHS K01 HL140216NIAID NIH HHS T32 AI114398NICHD NIH HHS T32 HD049311NIDDK NIH HHS P30 DK111022NIEHS NIH HHS P30 ES009089NIEHS NIH HHS R00 ES027022
6 · The paper itself

Abstract

Purpose of Review: Studies suggest ambient air pollution increases risk of individual-level adverse COVID-19 outcomes. Our review seeks to understand how air pollution influences adverse COVID-19 outcomes, by identifying how researchers accounted for cardiovascular morbidity, a predominant COVID-19 risk factor that is strongly linked to air pollution exposure. Recent Findings: Our review primarily consisted of retrospective cohorts from the US and Europe, that examined both historical and short-term air pollution. Studies typically found that air pollution was associated with greater risk of individual-level adverse COVID-19 outcomes and adjusted for cardiovascular morbidities as confounders. Few hypothesized cardiovascular morbidity as a mediator or effect modifier in this relationship. Summary: Improved understanding of cardiovascular morbidity's potential role as an effect modifier or mediator can help better explain the link between air pollution and COVID-19, in addition to identifying and assisting populations that may be at greater risk for adverse pandemic outcomes.

Indexed as

Air pollutionCardiovascular morbidityCOVID-19Environmental exposureInfectious disease severity

Identifiers

PMID41409639
PMCPMC12707389

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.