ArticleFrontiers in bioengineering and biotechnology2025
Allogenic Achilles-tendon-bone grafts enable more complete restoration of the native direct enthesis structure in the repair of chronic massive rotator cuff tears.
Article in Frontiers in bioengineering and biotechnology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Massive irreparable rotator cuff tears are difficult to restore when the tendon quality is poor, and the tendon retraction prevents complete repair. In such cases, tendon allograft bridging can restore continuity but cannot replicate the native tendon-bone interface. In this study, we evaluated an Achilles-tendon-bone block allograft (BTA) for anatomic tendon-bone interface reconstruction in a rabbit model of chronic massive rotator cuff tear. Thirty-six rabbits underwent bilateral infraspinatus tendon detachment, followed by repair after 3 weeks using direct suture (DS), tendon allograft without bone block (TA), or BTA. At 8 and 16 weeks, we assessed the magnetic-resonance-imaging-based tendon maturation (signal-to-noise quotient (SNQ)), micro-computed-tomography-based bone volume fraction (BV/TV) and histology, immunohistochemistry (COL I, II, X), and biomechanical-testing-based healing. The BTA group showed superior tendon continuity, significantly lower SNQ, and higher BV/TV than the DS and TA groups (
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