Evidence map›Paper›PMID 41409502›Full record

ArticleACS ES&T water2025

Tracking Age-Linked Antibiotic Resistance Patterns through Building-Level Wastewater Analysis.

Anna Pico-Tomàs, Alejandro Sanchís, Cristina Mejías-Molina, Marc Comas-Cufí, José Luis Balcázar, Sílvia Bofill-Mas, Helena Torrell, Núria Canela, Carles M Borrego, Lluís Corominas

Abstract read
In one paragraph

Article in ACS ES&T water, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Culture, qPCR, and genome-based surveillance ofFrontiers in microbiology · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Anna Pico-TomàsCatalan Institute for Water Research (ICRA-CERCA), Girona 17003, Spain.ORCID https://orcid.org/0000-0001-6511-6600
Alejandro SanchísCatalan Institute for Water Research (ICRA-CERCA), Girona 17003, Spain.
Cristina Mejías-MolinaLaboratori de Virus Contaminants de l'Aigua i d'Aliments, Departament de Genètica, Microbiologia i Estadística, Universitat de Barcelona, Barcelona 08028, Spain.ORCID https://orcid.org/0000-0003-1050-1178
Marc Comas-CufíDepartament d'Informàtica, Matemàtica Aplicada I Estadística, Universitat de Girona, Girona 17003, Spain.
José Luis BalcázarCatalan Institute for Water Research (ICRA-CERCA), Girona 17003, Spain.ORCID https://orcid.org/0000-0002-6866-9347
Sílvia Bofill-MasLaboratori de Virus Contaminants de l'Aigua i d'Aliments, Departament de Genètica, Microbiologia i Estadística, Universitat de Barcelona, Barcelona 08028, Spain.
Helena TorrellEurecat, Centre Tecnològic de Catalunya, Centre for Omic Sciences (COS), Unit Universitat Rovira i Virgili-EURECAT, Unique Scientific and Technical Infrastructures (ICTS), Reus 43204, Spain.
Núria CanelaEurecat, Centre Tecnològic de Catalunya, Centre for Omic Sciences (COS), Unit Universitat Rovira i Virgili-EURECAT, Unique Scientific and Technical Infrastructures (ICTS), Reus 43204, Spain.ORCID https://orcid.org/0000-0003-0261-2396
Carles M BorregoCatalan Institute for Water Research (ICRA-CERCA), Girona 17003, Spain.ORCID https://orcid.org/0000-0002-2708-3753
Lluís CorominasCatalan Institute for Water Research (ICRA-CERCA), Girona 17003, Spain.ORCID https://orcid.org/0000-0002-5050-2389

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Antimicrobial resistance (AMR) is a global health challenge, and monitoring different demographic populations can improve our understanding of its spread and prevalence in urban settlements. This study applies building-level wastewater-based epidemiology (WBE) to analyze the resistome and mobilome of age-segregated populations from an elementary school (School), a university residence (UnivRes), and an elderly care facility (ElderlyRes) all located in Girona (Catalonia, Spain). Metagenomic analyses were subsequently conducted to investigate differences in bacterial communities, antibiotic resistance genes (ARGs), and mobile genetic elements (MGEs). The results revealed age-linked variations in the relative abundance and diversity of ARGs. The wastewater collected at the School exhibited the highest abundance of ARGs, while the ElderlyRes showed the highest diversity. Furthermore, sequences affiliated with bacterial pathogens were more prevalent in samples from both the School and the ElderlyRes, emphasizing potential public health implications. Among the 12 bacterial genera most strongly correlated with ARGs (Pearson

Indexed as

age-groupsantimicrobial resistance (AMR)mobilomepassive samplingresistomesewerswastewater-based epidemiology (WBE)

Identifiers

PMID41409502
PMCPMC12707230

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.