ArticleJournal of radiosurgery and SBRT2025
Fractionated repeat Gamma Knife stereotactic radiosurgery for locally recurrent brain metastases.
Article in Journal of radiosurgery and SBRT, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Outcomes in long-term survivors treated with stereotactic cranial radiotherapy for brain metastases.Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al] · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Introduction: Survival of patients with brain metastases (BMs) is increasing. Consequently, local disease recurrence of previously treated BMs has become more prevalent. Stereotactic radiosurgery (SRS) has been employed as a salvage therapy; however, concerns over adverse radiation events (AREs) persist. Utilization of a fractionated approach may reduce AREs in this population. Methods: A retrospective review of locally recurrent BMs was conducted. The primary outcome was local control and AREs. Utilizing the Kaplan-Meier method, we analyzed the time to local control (LC) and overall survival (OS) for each recurrent lesion treated with SRS. Cox regression analysis was employed to examine predictors of LC and OS. Results: Our cohort consisted of 45 patients with a median age of 62 years [interquartile range (IQR): 56.3-68.0]. The median lesion volume at the time of repeat SRS was 3.3 cm Conclusion: Repeat fractionated SRS is safe and efficacious for locally recurrent BMs. Performance status and systemic disease control are predictors of OS in this population.
Indexed as
Identifiers
41409182PMC12707999What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.