Evidence map›Paper›PMID 41409148›Full record

ArticlebioRxiv : the preprint server for biology2025

Hyperactive Rac converts sublethal nibbling to lethal phagocytosis

Abhinava K Mishra, Lauren Penfield, Morgan Smith, Denise Montell

Abstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors.

Abhinava K MishraMolecular, Cellular, and Developmental Biology Department University of California, Santa Barbara, CA 93106.
Lauren PenfieldMolecular, Cellular, and Developmental Biology Department University of California, Santa Barbara, CA 93106.
Morgan SmithMolecular, Cellular, and Developmental Biology Department University of California, Santa Barbara, CA 93106.
Denise MontellMolecular, Cellular, and Developmental Biology Department University of California, Santa Barbara, CA 93106.

Funding

Spatiotemporal regulation of collective cell behaviors in Drosophila: Diversity Supplement for Predoctoral TrainingR01GM046425 · NIGMS · UNIVERSITY OF CALIFORNIA SANTA BARBARA · PI MONTELL, DENISE J. · 1996 to 2025
$11.7M
NIGMS NIH HHS R01 GM046425
6 · The paper itself

Abstract

The small GTPase Rac is an essential regulator of cell shape, migration, macropinocytosis and phagocytosis. We recently reported that expression of constitutively active Rac

Indexed as

CAR-MDrosophilaOvaryPhagocytosisTrogocytosis

Identifiers

PMID41409148
PMCPMC12707272

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.