Evidence map›Paper›PMID 41409093›Full record

ReviewAnesthesiology research and practice2025

A Systematic Review of Temporary Peripheral Nerve Stimulation for Postoperative Pain Management in Orthopedic Surgery.

Joshua C Harris, Chris J Pierson, Chaitanya Konda, Nitin B Jain

Abstract readReview
In one paragraph

Review in Anesthesiology research and practice, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Joshua C HarrisCollege of Medicine, Northeast Ohio Medical University, Rootstown, Ohio, USA, neomed.edu.ORCID https://orcid.org/0009-0001-2793-5733
Chris J PiersonUniversity of Texas Medical Branch Center for Addiction Sciences and Therapeutics, Galveston, Texas, USA.ORCID https://orcid.org/0000-0002-1671-5276
Chaitanya KondaDepartment of Physical Medicine & Rehabilitation, University of Texas Southwestern Medical Center, Dallas, Texas, USA, utsouthwestern.edu.ORCID https://orcid.org/0000-0002-1809-4346
Nitin B JainDepartment of Physical Medicine & Rehabilitation, University of Michigan, Ann Arbor, Michigan, USA, umich.edu.ORCID https://orcid.org/0000-0002-4362-8522

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background/Objectives: Over 18 million orthopedic procedures were performed in the United States in 2022 with pharmacological management being the primary mode of analgesia. Percutaneous neuromodulation in the form of temporary peripheral nerve stimulation (tPNS) may provide a new method of postsurgical analgesia devoid of systemic side effects and the potential for substance addiction. tPNS can also be used for chronic pain long after surgery. Methods: The initial literature search of PubMed/MEDLINE, Web of Science, and Cochrane was conducted on September 21, 2023, and repeated on May 23, 2025. Included studies had patients over 18 years of age with implanted tPNS in the first 2 years following orthopedic surgery of the knee, shoulder, hip, foot, or ankle. Results: Eleven articles of nine distinct studies were found: eight articles from six randomized trials and three articles from three case series. Seven publications assessed implanted tPNS in the acute perioperative phase, and four publications assessed implanted tPNS for chronic postoperative pain. This systematic review's aim was to compile current literature on the safety and efficacy of percutaneous tPNS both immediately after orthopedic surgery and for longer-term postsurgical persistent pain. This collection of evidence suggests using percutaneous tPNS is safe and may reduce pain and postoperative opioid consumption. Conclusions: This emerging treatment may reduce postoperative pain and opioid consumption, is safe, and warrants further robust trials. Future studies with robust, multimodal treatment designs are needed to specifically delineate the role of tPNS within the context of current pain management.

Identifiers

PMID41409093
PMCPMC12706534

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.