ArticleThe Journal of clinical endocrinology and metabolism2026
Elastography Enhances Diagnostic Accuracy of ACR TI-RADS in Thyroid Nodule Evaluation.
Article in The Journal of clinical endocrinology and metabolism, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
3 citing papers in PubMed.
- Elastography Enhances Diagnostic Accuracy of ACR TI-RADS in Thyroid Nodule Evaluation.The Journal of clinical endocrinology and metabolism · 2026Article
- The Role of Thyroid Elastography in Children with Type 1 Diabetes Mellitus or Celiac Disease Who Have Negative Thyroid Autoantibodies.Journal of clinical medicine · 2026Article
- Multimodal risk assessment of malignancy in thyroidology for nodules with indeterminate cytology.Revista da Associacao Medica Brasileira (1992) · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
contextThe American College of Radiology Thyroid Imaging Reporting and Data System (ACR TI-RADS) incorporates conventional grayscale ultrasonography (US) as the only imaging technique without considering the clinical and demographic characteristics of patients.
objectiveThis study assessed whether the addition of demographic information, color Doppler US (CDUS), and strain elastography (SE) could enhance malignancy risk stratification beyond the current ACR TI-RADS criteria.
methodsThis prospective study enrolled 556 adult patients with thyroid nodules 10 mm or greater who were referred for fine-needle aspiration (FNA) according to the ACR TI-RADS recommendations. All nodules underwent standardized US evaluations and vascularity assessments using CDUS and SE, with cytological analysis performed according to the Bethesda system. Surgical pathology was the gold standard for malignancy when available.
resultsApplying elastography ratio (ER) thresholds (>1.60, >0.44, and >0.54 for ACR TI-RADS categories 3, 4, and 5, respectively) as an additional criterion for FNA reduced the number of procedures from 501 to 260, without missing any malignant cases. Notably, elastography demonstrated an excellent discriminative performance in ACR TI-RADS 3 nodules (Youden index 0.994, area under the curve 0.994), supporting its value in improving risk stratification in this challenging, predominantly benign category.
conclusionIntegrating elastography into the ACR TI-RADS framework can optimize FNA utilization in the management of thyroid nodules by reducing the number of unnecessary aspiration biopsies.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.