Evidence map›Paper›PMID 41408902›Full record

ArticlePharmacology research & perspectives2026

Duplicate Prescription Patterns in Patients With Substance Use Disorders.

Johannes Heck, Benjamin Krichevsky, Martin Schulze Westhoff, Konstantin Fritz Jendretzky, Martin Klietz, Stephan Greten, Alexander Glahn, Stefan Bleich, Sebastian Schröder

Abstract read
In one paragraph

Article in Pharmacology research & perspectives, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Johannes HeckInstitute for Clinical Pharmacology, Hannover Medical School, Hannover, Germany.ORCID https://orcid.org/0000-0002-5382-3014
Benjamin KrichevskyInstitute for General Practice and Palliative Care, Hannover Medical School, Hannover, Germany.ORCID https://orcid.org/0000-0001-5899-0113
Martin Schulze WesthoffDepartment of Psychiatry, Social Psychiatry and Psychotherapy, Hannover Medical School, Hannover, Germany.ORCID https://orcid.org/0000-0003-3262-8137
Konstantin Fritz JendretzkyDepartment of Neurology, Hannover Medical School, Hannover, Germany.ORCID https://orcid.org/0000-0002-2953-0166
Martin KlietzDepartment of Neurology, Hannover Medical School, Hannover, Germany.ORCID https://orcid.org/0000-0002-3054-9905
Stephan GretenDepartment of Neurology, Hannover Medical School, Hannover, Germany.ORCID https://orcid.org/0000-0003-0638-8571
Alexander GlahnDepartment of Psychiatry, Social Psychiatry and Psychotherapy, Hannover Medical School, Hannover, Germany.ORCID https://orcid.org/0009-0005-5343-5280
Stefan BleichDepartment of Psychiatry, Social Psychiatry and Psychotherapy, Hannover Medical School, Hannover, Germany.ORCID https://orcid.org/0000-0001-5004-3824
Sebastian SchröderDepartment of Psychiatry, Social Psychiatry and Psychotherapy, Hannover Medical School, Hannover, Germany.ORCID https://orcid.org/0000-0003-0905-274X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study sought to investigate the frequency and characteristics of duplicate prescriptions (DPs) in psychiatric inpatients with substance use disorders using a DP classification that differentiates between appropriate DPs (ADPs) and potentially inappropriate DPs (PIDPs). The study was conducted as a monocentric retrospective cross-sectional study on the addiction-specific ward of the Department of Psychiatry, Social Psychiatry and Psychotherapy of Hannover Medical School, a large university hospital in northern Germany. The outcome measures were the nature and frequency of PIDPs compared with ADPs. Medication records of 1174 patients enrolled between January 2016 and December 2021 were reviewed. The median age of the study population (27.8% female) was 48 years (interquartile range (IQR) 39-56). Patients took a median of 4 drugs (IQR 2-6). 12.8% of the study population were exposed to at least one PIDP (at least one grade-1 PIDP: 12.0%; at least one grade-2 PIDP: 1.3%; at least one grade-3 PIDP: 0.3%). Sedatives were the most common cause of grade-1 PIDPs, while grade-2 PIDPs were elicited predominantly by opioids. Nearly one third of the study population (29.0%) displayed at least one ADP. Physicians treating patients with substance use disorders should carefully monitor for PIDPs, particularly PIDPs elicited by sedatives and opioids. Addressing PIDPs may help prevent adverse drug reactions and reduce drug expenses.

Indexed as

Drug PrescriptionsInappropriate PrescribingPractice Patterns, Physicians'Substance-Related DisordersAdultCross-Sectional StudiesFemaleGermanyHumansMaleMiddle AgedRetrospective Studiesaddiction psychiatrycross‐sectional studyduplicate prescriptionsmedication reviewpharmacotherapy safety

Identifiers

PMID41408902
PMCPMC12712343

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.