Evidence map›Paper›PMID 41408622›Full record

ArticleBMC public health2025

Quantifying the attributable burden of economic inequality on under-five mortality across ten African countries: a WHO HEAT-based analysis.

Alpha Umaru Bai-Sesay, Edward Ellie, Rosetta Doreen Jones, Mohamed S Bah, Chizaram Anselm Onyeaghala

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Article in BMC public health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

5 authors.

Alpha Umaru Bai-SesayMinistry of Health, National Public Health Agency, Freetown, Sierra Leone. umarbaisesay@gmail.com.ORCID http://orcid.org/0009-0008-6137-4870
Edward EllieMinistry of Health, National Public Health Agency, Freetown, Sierra Leone.
Rosetta Doreen JonesMinistry of Health, National Public Health Agency, Freetown, Sierra Leone.
Mohamed S BahMinistry of Health, National Public Health Agency, Freetown, Sierra Leone.
Chizaram Anselm OnyeaghalaDepartment of Internal Medicine, University of Port Harcourt Teaching Hospital, Port Harcourt, Nigeria.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionDespite global declines in under-five mortality, African countries continue to experience high rates, with socioeconomic disparities undermining progress toward Sustainable Development Goal 3.2. While wealth gradients in child survival are well documented, the proportion of deaths directly attributable to inequality remains poorly quantified across national contexts.

methodsWe conducted a cross-national secondary analysis using the WHO Health Equity Assessment Toolkit (HEAT) v.6.0. Data from ten African countries for the 2022 reference year were included, comprising a total study population of over 6.5 million live births. Under-five mortality rates were obtained from United Nations Inter-agency Group for Child Mortality Estimation (UN IGME) datasets, disaggregated by wealth quintile and sex. Inequality was assessed using Difference, Ratio, Population Attributable Risk, Population Attributable Fraction, Slope Index of Inequality, and Relative Index of Inequality.

resultsNational under-five mortality ranged from 38.0 per 1,000 live births in Rwanda to 117.3 in Niger, with all countries exceeding the SDG target of ≤ 25. Wealth gradients were present in all settings: the absolute difference between poorest and richest quintiles ranged from 11.3 (South Sudan) to 67.0 (Mali). Inequality-attributable burdens were highest in Mali (PAR - 41.9; PAF - 44.7%), Togo (PAR - 25.6; PAF - 42.5%), and Madagascar (PAR - 22.7; PAF - 34.5%). Gradient measures confirmed steep inequities in Mali and Togo (SII ≤ -56.3; RII 2.3). Male children had higher mortality, but sex-attributable fractions were negligible.

conclusionUp to 45% of under-five deaths in high-burden African countries are attributable to economic inequality. Embedding equity metrics into child survival strategies and targeting the poorest households are essential to accelerate progress toward ending preventable child deaths. Precision public health targeting the poorest quintiles is crucial to reducing preventable child deaths in Africa.

Indexed as

Child MortalityHealth Status DisparitiesInfant MortalitySocioeconomic FactorsAfricaChild, PreschoolFemaleHumansInfantInfant, NewbornMaleWorld Health OrganizationAfricaEconomic inequalityHealth equityPrecision public healthSocioeconomic disparitiesSustainable development goalsUnder-five mortalityWHO HEAT

Identifiers

PMID41408622
PMCPMC12821987

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.