Evidence map›Paper›PMID 41408529›Full record

SynthesisBMC surgery2025

Clinical performance of machine-learning algorithms to predict intraoperative hypotension: a meta-analysis.

Mahdi Faraji, Narges Norouzkhani, Anahid Bagheri Pour, Parnia Ghanad, Mobina Bayani, Melika Arab Bafrani, Alaleh Alizadeh, Sina Seyedipour, Niloofar Deravi, Masoud Noroozi and 1 more

Abstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in BMC surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Mahdi Faraji *Student research committee, school of medicine, Ardabil University of medical sciences, Ardabil, Iran.ORCID http://orcid.org/0009-0006-8618-231X
Narges Norouzkhani *Department of Health Information Technology, School of Management and Medical Informatics, Tabriz University of Medical Sciences, Tabriz, Iran.ORCID http://orcid.org/0000-0001-9734-9126
Anahid Bagheri Pour *Iran University of Medical Sciences, Tehran, Iran.ORCID http://orcid.org/0000-0001-9100-2981
Parnia GhanadStudent of Medicine, Zhejiang University, Hangzhou, China.ORCID http://orcid.org/0009-0003-8234-368X
Mobina BayaniStudent Research Committee, School of Medicine, Iran University Of Medical Sciences, Tehran, Iran.ORCID http://orcid.org/0009-0009-7492-4197
Melika Arab BafraniStudents' Scientific Research Center (SSRC), Tehran University of Medical Sciences, Tehran, Iran.ORCID http://orcid.org/0000-0002-3983-5844
Alaleh AlizadehStudent Research Committee, Faculty of Medicine, Mashhad Branch, Islamic Azad University, Mashhad, Iran.ORCID http://orcid.org/0000-0002-5421-1722
Sina SeyedipourJiroft University of Medical Sciences, Jiroft, Iran.ORCID http://orcid.org/0000-0002-5672-3545
Niloofar DeraviStudents Research Committee, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran.ORCID http://orcid.org/0000-0002-6965-6927
Masoud NorooziDepartment of Biomedical Engineering, Faculty of Engineering, University of Isfahan, Isfahan, Iran. 2000noroozi@gmail.com.ORCID http://orcid.org/0000-0002-6188-4650
Mohammad Amin EbrahimiStudent Research Committee, Sabzevar University of Medical Sciences, Sabzevar, Iran. Mohammadaminebrahimi105@gmail.com.ORCID http://orcid.org/0000-0001-7074-613X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND AND

aimIntraoperative hypotension is one of the most common surgical adverse effects, often associated with postoperative organ damage and complications. The use of non-invasive methods to predict hypotension during surgery could significantly reduce these complications. Recently developed machine learning algorithms show promise for improving the prediction of hypotension and enhancing detection during surgical procedures. Our meta-analysis aimed to evaluate the clinical performance of machine learning algorithms for predicting intraoperative hypotension.

methodA systematic search of PubMed, Scopus, Web of Science, and Google Scholar was conducted to retrieve articles published up to August 2024. Two independent researchers screened observational accuracy studies and also identified randomized controlled trials (RCTs) of AI-guided intraoperative management. Observational studies reporting diagnostic/prognostic accuracy metrics were included in the quantitative synthesis. After evaluating the quality of the studies, data extraction and analysis were accomplished.

resultsFive observational studies, including a total of 42,509 participants, were included in this study. Four studies were conducted in South Korea, and one in Taiwan. The machine learning algorithms applied in these studies for electrocardiography, basal systolic, and diastolic blood pressure. These studies assessed model performance based on sensitivity, specificity, and the area under the ROC curve (AUROC). The overall effect size, represented in a forest plot, showed specificity of 0.73 (95% CI: 0.67-0.79), sensitivity of 0.75 (95% CI: 0.71-0.79), and an AUROC of 0.83 (95% CI: 0.77-0.89). In addition, we identified RCTs evaluating AI/HPI-guided intraoperative management, due to heterogeneous endpoints.

conclusionMachine learning algorithms demonstrate acceptable performance and advantages in predicting intraoperative hypotension during surgical procedures. The application of these algorithms could be beneficial in future surgeries to reduce complications.

Indexed as

HypotensionIntraoperative ComplicationsMachine LearningAlgorithmsHumansArtificial intelligenceDeep learningIntraoperative hypotensionMachine learning

Identifiers

PMID41408529
PMCPMC12822040

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.