Evidence map›Paper›PMID 41408215›Full record

ArticleBMC cancer2025

Survival status and predictors of mortality among patients with cervical cancer in two oncology units in Northwest Ethiopia: a retrospective follow-up study.

Aragaw Tesfaw, Adamu Addissie, Eva Johanna Kantelhardt, Sefonias Getachew

Abstract read
In one paragraph

Article in BMC cancer, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it.

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4 · The record

Corrections and comments

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5 · Who and what money

Authors and funding

4 authors.

Aragaw TesfawDepartment of Epidemiology and Biostatistics, School of Public Health, Addis Ababa University, Addis Ababa, Ethiopia.ORCID http://orcid.org/0000-0002-2776-7469
Adamu AddissieDepartment of Epidemiology and Biostatistics, School of Public Health, Addis Ababa University, Addis Ababa, Ethiopia.
Eva Johanna Kantelhardt *Global and Planetary Health Working Group, Institute of Medical Epidemiology, Biostatistics and Informatics, Martin Luther University, Halle, Germany.ORCID http://orcid.org/0000-0001-7935-719X
Sefonias Getachew *Department of Epidemiology and Biostatistics, School of Public Health, Addis Ababa University, Addis Ababa, Ethiopia. sefonias.getachew@aau.edu.et.ORCID http://orcid.org/0000-0001-9506-1196

Funding

Else Kröner-Fresenius Foundation 2018_HA31SPGerman Federal Ministry of Research, Technology, and Space (BMFTR) 01KA2220BHospital Partnership via Deutsche Gesellschaft für Internationale Zusammenarbeit 81307397Wellcome Trust
6 · The paper itself

Abstract

backgroundCervical cancer is the most frequently diagnosed malignancy and a leading cause of death among women in sub-Saharan Africa, including Ethiopia. Despite its high mortality rate, little is known about survival outcomes and predictors of mortality for patients with cervical cancer in Northwest Ethiopia.

methodsA hospital based retrospective follow-up study was conducted among patients with cervical cancer diagnosed and treated from 1 February 2017 to 30 January 2022 at Felege Hiwot Hospital and University of Gondar Hospitals. Data were collected using a data abstraction checklist and telephone interviews. The Kaplan–Meier and the log-rank test were used to estimate and compare survival probabilities. Sensitivity analysis was performed assuming that patients lost to follow-up may have died 6 months after their last visit. The Cox regression model identified predictors of mortality with 95% confidence intervals, considering p < 0.05 as statistically significant.

resultsThe overall survival rate at 52 months of follow-up was 18.63%. The survival rates at 2, 3, and 4 years were 81.2%, 55.89%, and 37.26%, respectively. In the worst-case analysis, survival at 2, 3, and 4 years declined to 65%, 39%, and 26%, respectively. Significant predictors of mortality included age ≥ 50 years (AHR = 3.4, 95% CI: 1.80–6.48, p < 0.0001), HIV positivity (AHR = 2.9, 95% CI: 1.55–5.61, p = 0.001), Travel distance > 65 km (AHR = 1.9, 95% CI: 1.28–3.08, p = 0.002), no history of surgery (AHR = 2.8, 95% CI: 1.33–5.71, p = 0.006), and advanced stage at diagnosis ; Stage III: (AHR = 3.4, 95% CI: 1.95–5.79, p < 0.001), Stage IV (AHR = 6.7, 95% CI: 3.35–13.58, p < 0.001). However, residence, comorbidity, patient delay, anemia and menopausal status were not significant predictors of mortality (P > 0.05).

conclusionThe overall survival rate for patients with cervical cancer was low in this study. The identified predictors highlight the need to expand cervical cancer screening, diagnostic, and treatment services, especially in regions lacking radiotherapy facilities. Special focus should also be placed on elderly women, and women living with HIV.

Indexed as

Uterine Cervical NeoplasmsAdultAgedEthiopiaFemaleFollow-Up StudiesHumansKaplan-Meier EstimateMiddle AgedPrognosisRetrospective StudiesSurvival RateYoung AdultCervical cancerEthiopiaPredictorsSurvival

Identifiers

PMID41408215
PMCPMC12829144

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.