Evidence map›Paper›PMID 41408201›Full record

Observational studyBMC geriatrics2025

Detection of adverse events in older adults undergoing surgery using the IHI global trigger tool within the SURGE-Ahead project.

Jessica Wolf, Filippo Maria Verri, Thomas D Kocar, Dhayana Dallmeier, Raffael Cintean, Florian Gebhard, Christian Bolenz, Nuh Rahbari, Annabel S Mueller-Stierlin, Michael Denkinger and 1 more

Abstract readObservational StudyMulticenter Study
In one paragraph

Observational study in BMC geriatrics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Jessica WolfInstitute for Geriatric Research Ulm, Ulm University Medical Center, Ulm, Germany.
Filippo Maria VerriInstitute for Geriatric Research Ulm, Ulm University Medical Center, Ulm, Germany.
Thomas D KocarInstitute for Geriatric Research Ulm, Ulm University Medical Center, Ulm, Germany.
Dhayana DallmeierInstitute for Geriatric Research Ulm, Ulm University Medical Center, Ulm, Germany.
Raffael CinteanDepartment for Orthopedic Trauma, Ulm University Medical Center, Ulm, Germany.
Florian GebhardDepartment for Orthopedic Trauma, Ulm University Medical Center, Ulm, Germany.
Christian BolenzDepartment of Urology, Ulm University Medical Center, Ulm, Germany.
Nuh RahbariDepartment of General and Visceral Surgery, Ulm University Medical Center, Ulm, Germany.
Annabel S Mueller-StierlinInstitute for Epidemiology and Medical Biometry, Ulm University, Ulm, Germany.
Michael DenkingerInstitute for Geriatric Research Ulm, Ulm University Medical Center, Ulm, Germany.
Christoph LeinertInstitute for Geriatric Research Ulm, Ulm University Medical Center, Ulm, Germany. christoph.leinert@agaplesion.de.ORCID http://orcid.org/0000-0001-6638-1780

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe aim of this study was to identify the number, type and severity of adverse events (AE) and the factors associated with the (non)-occurrence of AE in older surgical inpatients within the SURGE-Ahead project.

methodsA retrospective chart review within a larger prospective observational study was conducted in three surgical departments of Ulm University Medical Center (trauma surgery, general surgery, urology). Patients undergoing inpatient elective or emergency surgery aged ≥ 70 years with an Identification of Seniors at Risk (ISAR) score ≥ 2 were included. A modified version of the Institute for Healthcare Improvement (IHI) Global Trigger tool (GTT) adapted to the geriatric cohort was utilized to identify AE during hospitalization and within 30 days after discharge. Binary logistic regression was conducted to identify factors associated with an adverse event-free treatment course.

resultsOf 174 included participants, 131 (75.3%) had at least one AE. In total 348 AEs were identified, which can be expressed as 155.9 AE per 1000 patient days or 200.0 AE per 100 admissions. In most cases the AE resulted in temporary harm requiring intervention (58.9%). Intra-/postoperative AE (43.8%) and nosocomial infections (18.9%) occurred most frequently. Younger age, shorter operation time and absence of frailty were significantly associated with an AE-free treatment course (AUC 0.81).

conclusionA notable number of AE were detected in the study population. The addition of the triggers „new Impairment of cognition/vigilance, fluctuating confusion” and “electrolyte disturbances” enhanced the efficacy of the IHI GTT in the geriatric population. Age, frailty status and operation time might predict the need for geriatric co-management.

trial registrationGerman clinical trials registry (Deutsches Register für klinische Studien, DRKS00030684), registered on 21st November 2022.

Indexed as

Postoperative ComplicationsSurgical Procedures, OperativeAgedAged, 80 and overFemaleHumansMaleProspective StudiesRetrospective StudiesAdverse eventGeriatric co-managementGeriatricsIHI global trigger tool (GTT)Surgery

Identifiers

PMID41408201
PMCPMC12857066

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.