Evidence map›Paper›PMID 41407974›Full record

ArticleEuropean journal of nuclear medicine and molecular imaging2026

Preclinical evaluation of

Yi Liu, Xiao Wang, Xiaoyu Pan, Xuan Huang, Simin He, Jianping Zhang, Xiaoping Xu, Shaoli Song

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in European journal of nuclear medicine and molecular imaging, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. The novel [RSC advances · 2026
    Article
  2. Article
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Yi Liu *Department of Nuclear Medicine, Fudan University Shanghai Cancer Center, Shanghai, 200032, China.
Xiao Wang *Department of Nuclear Medicine, Fudan University Shanghai Cancer Center, Shanghai, 200032, China.
Xiaoyu Pan *Department of Nuclear Medicine, Fudan University Shanghai Cancer Center, Shanghai, 200032, China.
Xuan HuangDepartment of Nuclear Medicine, Fudan University Shanghai Cancer Center, Shanghai, 200032, China.
Simin HeDepartment of Nuclear Medicine, Fudan University Shanghai Cancer Center, Shanghai, 200032, China.
Jianping ZhangDepartment of Nuclear Medicine, Fudan University Shanghai Cancer Center, Shanghai, 200032, China.
Xiaoping XuDepartment of Nuclear Medicine, Fudan University Shanghai Cancer Center, Shanghai, 200032, China. xxp0012@ustc.edu.
Shaoli SongDepartment of Nuclear Medicine, Fudan University Shanghai Cancer Center, Shanghai, 200032, China. shaoli-song@163.com.ORCID 0000-0003-2544-7522

Funding

National Isotope Engineering Technology Research Center Funding GJTWSGCZX-202306National Natural Science Foundation of China 12275057National Natural Science Foundation of China 82102097Shanghai Oriental Talents Program Youth Project SSF828085
6 · The paper itself

Abstract

purposeAG10 is a molecule that can bind to the thyroxine (T4) binding pocket of transthyretin (TTR). The reversible association between the hydrophilic peptides and TTR using AG10 could increase the circulation half-life (t

methodsLysine was used as a linker for the conjugation of PSMA-617 and AG10 to synthesize AG10-PSMA-617 (AP-01). AP-01 was labeled with

resultsPSMA-617 was successfully conjugated with AG10 using lysine as the linker and labeled with

conclusionIn this study, AP-01 was successfully synthesized.

Indexed as

Antigens, SurfaceDipeptidesGallium RadioisotopesGene Expression Regulation, NeoplasticGlutamate Carboxypeptidase IIHeterocyclic Compounds, 1-RingLutetiumProstatic NeoplasmsRadioisotopesRadiopharmaceuticalsAnimalsCell Line, TumorHumansIsotope LabelingMaleMiceAntigens, SurfaceDipeptidesFOLH1 protein, humanGallium-68Gallium RadioisotopesGlutamate Carboxypeptidase IIHeterocyclic Compounds, 1-RingLutetiumLutetium-177RadioisotopesRadiopharmaceuticals177Lu-AP-01AG10Precision medicineProstate cancerPSMA

Identifiers

PMID41407974
PMCPMC13121540

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.