ArticlePediatric research2026
Growth outcome trends after necrotizing enterocolitis in preterm infants across changes in nutritional practices.
Article in Pediatric research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Beyond survival: growth trajectories in necrotizing enterocolitis.Pediatric research · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundTo investigated trends in postnatal and after-discharge growth outcomes during changes in nutritional practices over time in extremely preterm infants with necrotizing enterocolitis (NEC).
methodsThis multicenter cohort study enrolled 3046 infants born at <28 weeks' gestation between 2006 and 2019. Growth trajectories by z-scores of body weight (zBW) and head circumference (zHC) from neonatal-intensive-care-unit discharge to corrected age 24 months were analyzed across NEC severity (no/stage-I NEC, stage-II, stage-III) and epochs (1: 2006-2009; 2: 2010-2014; 3: 2015-2019) after propensity-score-matching (PSM).
resultsThe PSM cohort included the stage-II (n = 221), stage-III (n = 103), and no/stage-I NEC (n = 972) groups. The stage-II/III NEC groups had significantly lower zBW and zHC compared to the no/stage-I NEC group at discharge during Epochs 2 and 3. After discharge, the stage-II NEC group achieved comparable zBW and zHC to the no/stage-I NEC group by 6-24 months in all epochs. In contrast, the stage-III NEC group displayed zBW improvement between 12 and 24 months in Epochs 2 and 3, but continued to have lower zHC from discharge to 24 months throughout all epochs.
conclusionsAs the general nutritional practices advanced, preterm infants with stage-III NEC consistently exhibited head growth deficits through 24 months of age. IMPACT: For infants born extremely preterm in the three epochs of evolution in nutritional practices: By discharge, infants with stage-II or stage-III NEC had significantly lower mean z-scores of body weight and head circumference compared to those with no/stage-I NEC. By age 6 to 24 months, infants with stage-II NEC caught up in weight and head growth with the no/stage-I NEC group. Infants with stage-III NEC caught up in weight growth with the no/stage-I NEC group between age 12 and 24 months, but persistently lagged behind in head growth up to 24 months throughout all epochs.
Indexed as
Identifiers
41407890What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.