ArticleNature2026
Human assembloids recapitulate periportal liver tissue in vitro.
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Article in Nature, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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17citing papers in PubMed
–field-weighted citation impact
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
17 citing papers in PubMed.
- Transient culture of adult human hepatocytes as organoids improves engineered liver engraftment.Biomaterials · 2027Article
- The liver in diabetes: current state and future perspectives.Diabetologia · 2026Review
- Biofabrication for spatial control of multiscale biological crosstalk in tissue models.npj biomedical innovations · 2026Review
- Integrated mesenchymal and extracellular cues drive bioengineered liver tissue formation and function.Materials today. Bio · 2026Article
- Synthetic developmental engineering of human liver organogenesis.Development (Cambridge, England) · 2026Review
- Cholangiocyte biology in primary sclerosing cholangitis and other cholangiopathies: pathogenesis, clinical insights, and experimental tools.Physiological reviews · 2026Review
- New developments and applications of human organoids.Nature reviews. Molecular cell biology · 2026Review
- The hepatic portal area in homeostasis and disease.Clinical and molecular hepatology · 2026Article
- A 3D In Vitro Model of the Human Hepatobiliary Junction.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- Liver organoids for chemical risk assessment: biological fidelity, standardization, and context-of-use frameworks.Archives of pharmacal research · 2026Review
- Integrating CRISPR genome editing with liver organoid and hiPSC-derived microfluidic platforms to model metabolic dysfunction-associated steatotic liver disease.Biochemistry and biophysics reports · 2026Review
- Synthetic control of implanted engineered liver tissue growth.Science advances · 2026Article
- New approach methodologies to model liver fibrosis in metabolic dysfunction-associated steatohepatitis.BMB reports · 2026Review
- Regulated necrosis at the crossroads of liver inflammation and cancer development.Nature reviews. Gastroenterology & hepatology · 2026Review
- Generation of proliferative hESC-derived grape-clustered hepatocyte organoids with multipolar architecture as regenerative counterpart via synergy of YAP and IGF2 pathways.Cell death & disease · 2026Article
- Synergistic immunotherapeutic effects of irreversible electroporation and CAR-NK cell therapy against hepatocellular carcinoma.Signal transduction and targeted therapy · 2026Article
- Reconstructing Liver Fibrosis: 3D Human Models, Microbiome Interfaces, and Therapeutic Innovation.Current issues in molecular biology · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
21 authors.
Lei Yuan *Max Planck Institute of Molecular Cell Biology and Genetics, Dresden, Germany.ORCID 0009-0006-1378-7000
Sagarika Dawka *Max Planck Institute of Molecular Cell Biology and Genetics, Dresden, Germany.ORCID 0009-0003-3553-5726
Yohan Kim *Max Planck Institute of Molecular Cell Biology and Genetics, Dresden, Germany.ORCID 0000-0002-4009-1694
Anke Liebert *Max Planck Institute of Molecular Cell Biology and Genetics, Dresden, Germany.ORCID 0000-0002-5849-6147
Fabian RostMax Planck Institute of Molecular Cell Biology and Genetics, Dresden, Germany.ORCID 0000-0001-6466-2589
Robert Arnes-BenitoMax Planck Institute of Molecular Cell Biology and Genetics, Dresden, Germany.
Franziska BaenkeDepartment of Visceral, Thoracic and Vascular Surgery, Medical Faculty and University Hospital Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany.
Christina GötzDepartment of Hepatobiliary Surgery and Visceral Transplantation, Clinic for Visceral, Transplant, Thoracic and Vascular Surgery, Leipzig University Medical Center, Leipzig, Germany.ORCID 0000-0002-8060-1599
David Long Hin TsangMax Planck Institute of Molecular Cell Biology and Genetics, Dresden, Germany.ORCID 0000-0002-1594-2987
Andrea SchuhmannMax Planck Institute of Molecular Cell Biology and Genetics, Dresden, Germany.
Anna ShevchenkoMax Planck Institute of Molecular Cell Biology and Genetics, Dresden, Germany.ORCID 0009-0008-6157-4442
Roberta Rezende de CastroMax Planck Institute of Molecular Cell Biology and Genetics, Dresden, Germany.
Seunghee KimDepartment of Surgery, Hanyang University College of Medicine, Seoul, South Korea.
Aleksandra SljukicMax Planck Institute of Molecular Cell Biology and Genetics, Dresden, Germany.
Anna M DowbajMax Planck Institute of Molecular Cell Biology and Genetics, Dresden, Germany.ORCID 0000-0002-6278-8011
Andrej ShevchenkoMax Planck Institute of Molecular Cell Biology and Genetics, Dresden, Germany.ORCID 0000-0002-5079-1109
Daniel SeehoferDepartment of Hepatobiliary Surgery and Visceral Transplantation, Clinic for Visceral, Transplant, Thoracic and Vascular Surgery, Leipzig University Medical Center, Leipzig, Germany.
Dongho ChoiDepartment of Surgery, Hanyang University College of Medicine, Seoul, South Korea.
Georg DammDepartment of Hepatobiliary Surgery and Visceral Transplantation, Clinic for Visceral, Transplant, Thoracic and Vascular Surgery, Leipzig University Medical Center, Leipzig, Germany.ORCID 0000-0002-2104-8076
Daniel E StangeDepartment of Visceral, Thoracic and Vascular Surgery, Medical Faculty and University Hospital Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany.ORCID 0000-0003-4246-2230
Meritxell HuchMax Planck Institute of Molecular Cell Biology and Genetics, Dresden, Germany. huch@mpi-cbg.de.ORCID 0000-0002-1545-5265
Funding
Max Planck Society
Abstract
The development of complex multicellular human in vitro systems holds great promise for modelling disease and advancing drug discovery and tissue engineering
Indexed as
HepatocytesLiverModels, BiologicalOrganoidsAnimalsDisease Models, AnimalFemaleHumansLiver Cirrhosis, BiliaryMaleMesodermMice
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.