Evidence map›Paper›PMID 41407855›Full record

ArticleNature2026

Spatiotemporal cellular map of the developing human reproductive tract.

Valentina Lorenzi, Cecilia Icoresi-Mazzeo, Charlotte Cassie, Nadav Yayon, Elias R Ruiz-Morales, Carmen Sancho-Serra, Ryan Colligan, Frederick C K Wong, Magda Marečková, Elizabeth Tuck and 16 more

Abstract read
In one paragraph

Article in Nature, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. HMMRCell discovery · 2026
    Article
  3. Review
  4. Neonatal diethylstilbestrol exposure disrupts uterine epithelial apical-basal polarity and partial EMT state.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  5. Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

26 authors.

Valentina Lorenzi *Wellcome Sanger Institute, Cambridge, UK.ORCID 0000-0002-3111-4006
Cecilia Icoresi-Mazzeo *Wellcome Sanger Institute, Cambridge, UK.ORCID 0000-0003-4728-3194
Charlotte CassieWellcome Sanger Institute, Cambridge, UK.ORCID 0009-0000-3432-1126
Nadav YayonWellcome Sanger Institute, Cambridge, UK.
Elias R Ruiz-MoralesWellcome Sanger Institute, Cambridge, UK.ORCID 0000-0002-5801-6190
Carmen Sancho-SerraWellcome Sanger Institute, Cambridge, UK.
Ryan ColliganWellcome Sanger Institute, Cambridge, UK.ORCID 0009-0009-0005-8636
Frederick C K WongWellcome Sanger Institute, Cambridge, UK.ORCID 0000-0002-0503-4360
Magda MarečkováWellcome Sanger Institute, Cambridge, UK.
Elizabeth TuckWellcome Sanger Institute, Cambridge, UK.ORCID 0000-0002-1837-7549
Kenny RobertsWellcome Sanger Institute, Cambridge, UK.ORCID 0000-0001-6155-0821
Tong LiWellcome Sanger Institute, Cambridge, UK.ORCID 0000-0002-8240-4476
Marc-Antoine JacquesEuropean Bioinformatics Institute-European Molecular Biology Laboratory, Cambridge, UK.ORCID 0000-0002-8224-9285
James AshcroftWellcome Sanger Institute, Cambridge, UK.ORCID 0000-0003-2964-5032
Xiaoling HeWellcome-MRC Cambridge Stem Cell Institute, University of Cambridge, Cambridge, UK.ORCID 0009-0004-1002-8418
Berta CrespoHDBR, Great Ormond Street Institute of Child Health, University College London, London, UK.ORCID 0000-0003-0006-009X
Batuhan CakirWellcome Sanger Institute, Cambridge, UK.ORCID 0000-0003-4513-606X
Simon MurrayWellcome Sanger Institute, Cambridge, UK.ORCID 0009-0007-0787-1051
Yong GuWellcome Sanger Institute, Cambridge, UK.
Alexander V PredeusWellcome Sanger Institute, Cambridge, UK.ORCID 0000-0002-2750-1599
Martin PreteWellcome Sanger Institute, Cambridge, UK.ORCID 0000-0002-5946-821X
Iva KelavaWellcome Sanger Institute, Cambridge, UK.
Roger BarkerWellcome-MRC Cambridge Stem Cell Institute, University of Cambridge, Cambridge, UK.ORCID 0000-0001-8843-7730
Luz Garcia-AlonsoWellcome Sanger Institute, Cambridge, UK. lg18@sanger.ac.uk.ORCID 0000-0002-7863-9619
John C MarioniWellcome Sanger Institute, Cambridge, UK. marioni@ebi.ac.uk.ORCID 0000-0001-9092-0852
Roser Vento-TormoWellcome Sanger Institute, Cambridge, UK. rv4@sanger.ac.uk.ORCID 0000-0002-9870-8474

Funding

Wellcome Trust
6 · The paper itself

Abstract

The human reproductive tract is essential for species perpetuation and overall health. Its development involves complex processes of sex specification, tissue patterning and morphogenesis, the disruption of which can cause lifelong issues, including infertility

Indexed as

Spatio-Temporal AnalysisEpitheliumFallopian TubesFemaleGene Expression Regulation, DevelopmentalGenes, HomeoboxHumansMaleMullerian DuctsOrganoidsPenisSex CharacteristicsSingle-Cell AnalysisTranscription FactorsUterusTranscription Factors

Identifiers

PMID41407855
PMCPMC12893920

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.