Evidence map›Paper›PMID 41407667›Full record

ArticleNature communications2025

Chromosome-level assembly and analysis of three hydroxy fatty acid-producing Physaria species.

Shuo Wang, Ruyi Fan, Mengling Zhang, Zhi-Wei Zhou, Weibo Xie, Jinpeng Wang, Edgar B Cahoon, Guanqun Chen, Shaoping Lu, Chaofu Lu and 2 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Nature communications, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Shuo Wang *National Key Laboratory of Crop Genetic Improvement, Hubei Hongshan Laboratory, Huazhong Agricultural University, Wuhan, Hubei, China.
Ruyi Fan *National Key Laboratory of Crop Genetic Improvement, Hubei Hongshan Laboratory, Huazhong Agricultural University, Wuhan, Hubei, China.
Mengling ZhangNational Key Laboratory of Crop Genetic Improvement, Hubei Hongshan Laboratory, Huazhong Agricultural University, Wuhan, Hubei, China.
Zhi-Wei ZhouNational Key Laboratory of Crop Genetic Improvement, Hubei Hongshan Laboratory, Huazhong Agricultural University, Wuhan, Hubei, China.
Weibo XieNational Key Laboratory of Crop Genetic Improvement, Hubei Hongshan Laboratory, Huazhong Agricultural University, Wuhan, Hubei, China.ORCID http://orcid.org/0000-0002-2768-3572
Jinpeng WangDepartment of Bioinformatics, School of Life Sciences, North China University of Science and Technology, Tangshan, Hebei, China.ORCID http://orcid.org/0000-0002-2253-7752
Edgar B CahoonCenter for Plant Science Innovation and Department of Biochemistry, University of Nebraska‑Lincoln, Lincoln, NE, USA.ORCID http://orcid.org/0000-0002-7277-1176
Guanqun ChenDepartment of Agricultural, Food and Nutritional Science, University of Alberta, Edmonton, AB, Canada.ORCID http://orcid.org/0000-0001-5790-3903
Shaoping LuNational Key Laboratory of Crop Genetic Improvement, Hubei Hongshan Laboratory, Huazhong Agricultural University, Wuhan, Hubei, China. lusp@mail.hzau.edu.cn.ORCID http://orcid.org/0000-0001-9327-6193
Chaofu LuDepartment of Plant Sciences and Plant Pathology, Montana State University, Bozeman, MT, USA. clu@montana.edu.ORCID http://orcid.org/0000-0001-6901-7490
Ling-Ling ChenYazhouwan National Laboratory, Sanya, Hainan, China. chenlingling@yzwlab.cn.ORCID http://orcid.org/0000-0002-3005-526X
Liang GuoNational Key Laboratory of Crop Genetic Improvement, Hubei Hongshan Laboratory, Huazhong Agricultural University, Wuhan, Hubei, China. guoliang@mail.hzau.edu.cn.ORCID http://orcid.org/0000-0001-7191-5062

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Several Physaria species (Brassicaceae) produce abundant hydroxy fatty acids in their seeds, with industrial applications. Here, we report three chromosome-level genomes of Physaria species: P. lindheimeri, P. pallida and P. fendleri, with sizes of 344 Mb, 329 Mb and 452 Mb, respectively. Comparative genome analysis reveals that these three Physaria species diverged from Arabidopsis thaliana approximately 14.10-14.46 million years ago and underwent two consecutive Physaria-specific whole-genome duplication events. Their centromeres harbor an 111-bp satellite repeat and two retrotransposon classes (Gypsy/CRM, Copia/Ale). Transcriptomic analysis identifies seed-highly expressed lipid synthesis genes potentially underlying unique fatty acid profiles. Furthermore, we pinpoint the two residues in FAH12 variants that cause the disparity in hydroxylation activity among the three Physaria species. Taken together, this study provides important genomic resources for investigating the evolution of Physaria species and developing industrial oil crops for sustainable production of hydroxy fatty acids.

Indexed as

BrassicaceaeChromosomes, PlantFatty AcidsGenome, PlantArabidopsisEvolution, MolecularPhylogenyPlant ProteinsRetroelementsSeedsFatty AcidsPlant ProteinsRetroelements

Identifiers

PMID41407667
PMCPMC12749981

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.