Evidence map›Paper›PMID 41407396›Full record

Trial reportBMJ open respiratory research2025

Exploring the predictors and barriers to accepting smoking cessation support within a targeted lung health check setting.

Parris J Williams, Sara C Buttery, Alexis Perkins, Keir Elmslie James Philip, Ley T Chan, Jane Derbyshire, Emily C Bartlett, Anand Devaraj, Michael I Polkey, Anthony A Laverty and 1 more

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in BMJ open respiratory research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Parris J WilliamsNational Heart and Lung Institute, Imperial College London, London, UK parris.williams@imperial.ac.uk.ORCID http://orcid.org/0000-0001-8027-1879
Sara C ButteryNational Heart and Lung Institute, Imperial College London, London, UK.ORCID http://orcid.org/0000-0001-9410-414X
Alexis PerkinsImperial College London National Heart and Lung Institute, London, UK.
Keir Elmslie James PhilipNational Heart and Lung Institute, Imperial College London, London, UK.ORCID http://orcid.org/0000-0001-9614-3580
Ley T ChanNational Heart and Lung Institute, Imperial College London, London, UK.
Jane DerbyshireRM Partners, London, London, UK.
Emily C BartlettRoyal Brompton Hospital, London, UK.
Anand DevarajDepartment of Radiology, Royal Brompton Hospital, London, UK.
Michael I PolkeyNIHR Respiratory BRU, Royal Brompton Hospital and National Heart and Lung Institute, London, UK.
Anthony A LavertyDepartment of Primary Care and Public Health, Imperial College, London, UK.ORCID http://orcid.org/0000-0003-1318-8439
Nicholas S HopkinsonNational Heart and Lung Institute, Imperial College London, London, UK.ORCID http://orcid.org/0000-0003-3235-0454

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe Quit Smoking Lung Health Intervention Trials (QuLIT-1 and -2), and other studies, show that providing immediate smoking cessation support within lung cancer screening services substantially improves quit rates. However, in the QuLIT2 trial, only around half of those offered smoking cessation support actually accepted it. Understanding what underpins this and how to facilitate higher engagement would enhance the health impact of the Targeted Lung Health Check programme.

methodWe compared characteristics of participants in the intervention arm of the QuLIT-2 study who accepted or declined the offer of smoking cessation support and conducted thematic analysis of interviews with 15 smokers who had declined it.

resultsOf 152 study participants randomised to smoking cessation support (61.3±4.8 years, 42% female), 80 declined the offer and 15 dropped out after the initial session, leaving 57 'accepters'. Accepters were more likely to be female (53% vs 40% adjusted OR (AOR): 3.30, 95% CI 1.47 to 7.48), younger (AOR: 0.90 (0.80 to 0.98)) and were more likely to live in areas of medium or low deprivation (AOR: 5.30 (1.86 to 22.85)). Thematic analysis of the interviews revealed four main barriers to acceptance: (1) mental health as a barrier, (2) personal beliefs about quitting smoking, (3) perceived usefulness of the interventions offered and (4) past negative experiences of smoking cessation support. DISCUSSION: Cessation services embedded in lung screening programmes need to anticipate barriers such as mental health concerns, past unsuccessful quit attempts experiences and personal beliefs. Efforts should be made to design and offer equitable services that meet the needs of this population. TRIAL REGISTRATION NUMBER: ISRCTN12455871.

Indexed as

Lung NeoplasmsPatient Acceptance of Health CareSmoking CessationAgedEarly Detection of CancerFemaleHumansMaleMiddle AgedLung CancerTobacco and the lung

Identifiers

PMID41407396
PMCPMC12716546

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.