ArticleJournal of Korean Neurosurgical Society2026
Why Is a Large-Bore Catheter Necessary in Large Vessel Occlusion from a Biomechanical Perspective?
Article in Journal of Korean Neurosurgical Society, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Beyond endovascular limits: open surgical management of bilateral giant petrocavernous internal carotid artery aneurysms in a pediatric patient.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
Abstract
objectiveAspiration thrombectomy is a widely adopted treatment for acute ischemic stroke due to large vessel occlusion. Among several technical factors, the diameter of the aspiration catheter plays a critical role in determining thrombus fixation, aspiration efficiency, and overall procedural success. This study aimed to investigate the biomechanical effects of a larger catheter diameter on thrombus behavior and vessel wall response during aspiration thrombectomy.
methodsFinite element analysis was employed to simulate aspiration using three clinically relevant aspiration catheters with different diameters. Thrombi of two lengths and two compositions, varying in red blood cell content, were modeled to reflect clinical variability. Mechanical outcomes, including thrombus deformation, internal stress distribution, and vessel wall loading, were analyzed under standardized aspiration pressure conditions.
results0.080- and 0.084-inch large-bore catheters produced greater thrombus deformation and internal stress than the 0.072-inch catheter, particularly in softer thrombi with higher red blood cell content. In both 3 and 5 mm thrombi with red blood cells, deformation increased by approximately 12.3% with the 0.084-inch catheter compared to the 0.072-inch catheter. These changes indicate improved clot engagement and aspiration efficiency, while vessel stress remained within physiological limits. This mechanical advantage is partly due to greater luminal occupancy, with the 0.084-inch catheter occupying 65.6% of the vessel lumen, about 14% more than the 0.072-inch catheter.
conclusionLarge-bore aspiration catheters can enhance thrombus fixation and aspiration performance without compromising vascular integrity. These findings support the broader clinical use of larger-bore catheters in patients with large artery occlusion, particularly in cases requiring strong clot engagement and efficient recanalization.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.