Evidence map›Paper›PMID 41406464›Full record

ArticleJMIR public health and surveillance2025

Community-Based BMI Screening for Overweight and Obesity in Adults Aged 35 Years and Older in Malaysia: Regression Discontinuity Analysis.

Wenjin Chen, Zhoutao Zheng, Shiyu Zhang, Mohd Roshidi Ismail, Pascal Geldsetzer, Till Bärnighausen, Chen Wang, Simiao Chen, Tin Tin Su

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Article in JMIR public health and surveillance, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

9 authors.

Wenjin ChenChinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China.ORCID 0009-0003-8506-2701
Zhoutao ZhengChinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China.ORCID 0009-0008-0872-6523
Shiyu ZhangChinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China.ORCID 0000-0003-2988-5781
Mohd Roshidi IsmailSouth East Asia Community Observatory (SEACO), Global Population Health, Jeffrey Cheah School of Medicine and Health Sciences, Monash University, Subang Jaya, Selangor, Malaysia.ORCID 0000-0002-0698-7964
Pascal GeldsetzerStanford University, California, CA, United States.ORCID 0000-0002-8878-5505
Till BärnighausenChinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China.ORCID 0000-0002-4182-4212
Chen WangChinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China.ORCID 0000-0001-7857-5435
Simiao ChenChinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China.ORCID 0000-0003-0555-2157
Tin Tin SuHeidelberg University, Heidelberg, Baden-Württemberg, Germany.ORCID 0000-0003-0387-6406

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundOverweight and obesity are major risk factors for numerous chronic diseases, requiring effective prevention and intervention strategies. Community-based BMI screening may enhance awareness of weight status, but its effectiveness remains uncertain.

objectiveThis study aimed to rigorously evaluate the long-term causal effects of community-based BMI screening with a light-touch intervention in Malaysia using a regression discontinuity design (RDD).

methodsUsing data from 2 waves (2013 and 2018) of a Malaysian population-based cohort study (N=6561), we applied a sharp RDD to estimate the causal effects of community-based BMI screening on health outcomes for individuals near the BMI threshold. Participants were aged 35 years or older and completed both follow-ups. The exposure was BMI screening with a light-touch intervention, including height and weight measurement, feedback on results, and referral card distribution. Main outcomes were BMI, blood pressure, and random blood glucose 5 years post intervention, along with health behaviors, health care use, and mental health status.

resultsBMI screening and intervention showed no significant impact on BMI after 5 years (0.4 kg/m², 95% CI -0.2 to 0.9, P=.16). Results remained robust after adjusting for covariates (eg, 0.4 kg/m², 95% CI -0.1 to 0.9 with age and sex; 0.5 kg/m², 95% CI -0.1 to 1.0 with demographic covariates) and modifying functional forms (0.4 kg/m², 95% CI -0.2 to 1.1 with quadratic specification). Robustness was also confirmed across different bandwidths, placebo tests, "donut" RDD, and when treating age as either a continuous or categorical variable. Interaction analysis revealed almost no substantial heterogeneity effects. Mechanism analysis and secondary outcomes indicated no significant effects on health behaviors (including smoking, physical activity, diet, and sedentary behavior), health care use (screening, diagnosis, and medication treatment of hypertension and diabetes), mental health outcomes (anxiety, depression, and stress levels), or cardiovascular risk factors (systolic blood pressure, diastolic blood pressure, random blood glucose; eg, systolic blood pressure showed a nonsignificant change of 0.2, 95% CI -3.5 to 4.0 mm Hg). These findings should be interpreted cautiously, as this study was sufficiently powered to detect larger, clinically meaningful changes but may have lacked power to identify more modest effects.

conclusionsThis study is the first to assess the causal effects of population-based BMI screening on long-term health outcomes in a Southeast Asian population. The findings suggest that merely informing individuals of their overweight or obese status and implementing light-touch interventions are insufficient to significantly reduce BMI or drive sustained behavior change. Nonetheless, the results do not exclude the possibility of short-term effects, and more frequent or sustained light-touch interventions may still be effective. Future studies should design more intensive interventions and include larger sample sizes.

Indexed as

Body Mass IndexMass ScreeningObesityOverweightAdultAgedCohort StudiesFemaleHumansMalaysiaMaleMiddle AgedRegression AnalysisBMIregression discontinuity designscreening

Identifiers

PMID41406464
PMCPMC12756664

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.