Article in Science translational medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registry
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what money
Authors and funding
20 authors.
Ankit UniyalDepartment of Anesthesiology and Critical Care Medicine, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.ORCID 0000-0003-3327-4166
Niyada HinJohns Hopkins Drug Discovery and Department of Neurology, Johns Hopkins University, Baltimore, MD 21205, USA.ORCID 0009-0003-8475-2591
Chi ZhangDepartment of Anesthesiology and Critical Care Medicine, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.ORCID 0000-0001-7306-2243
Qian XuSolomon H. Snyder Department of Neuroscience, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.ORCID 0000-0001-6227-7644
Qian HuangDepartment of Anesthesiology and Critical Care Medicine, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.
Ilyas BerhaneJohns Hopkins Drug Discovery and Department of Neurology, Johns Hopkins University, Baltimore, MD 21205, USA.
Ajit G ThomasJohns Hopkins Drug Discovery and Department of Neurology, Johns Hopkins University, Baltimore, MD 21205, USA.ORCID 0000-0001-5922-5050
John MaragakisJohns Hopkins Drug Discovery and Department of Neurology, Johns Hopkins University, Baltimore, MD 21205, USA.ORCID 0009-0000-6135-2331
Sadakatali GoriJohns Hopkins Drug Discovery and Department of Neurology, Johns Hopkins University, Baltimore, MD 21205, USA.ORCID 0000-0003-0840-829X
Jing LiuDepartment of Anesthesiology and Critical Care Medicine, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.ORCID 0000-0001-7843-3883
Qin ZhengDepartment of Anesthesiology and Critical Care Medicine, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.ORCID 0000-0002-4373-1191
Xiang CuiDepartment of Anesthesiology and Critical Care Medicine, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.ORCID 0000-0002-3029-5829
Qi PengSolomon H. Snyder Department of Neuroscience, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.
Jieru WanDepartment of Anesthesiology and Critical Care Medicine, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.
Rana RaisJohns Hopkins Drug Discovery and Department of Neurology, Johns Hopkins University, Baltimore, MD 21205, USA.ORCID 0000-0003-4059-2453
Barbara S SlusherJohns Hopkins Drug Discovery and Department of Neurology, Johns Hopkins University, Baltimore, MD 21205, USA.ORCID 0000-0001-9814-4157
Srinivasa N RajaDepartment of Anesthesiology and Critical Care Medicine, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.ORCID 0000-0001-7991-7636
Xinzhong DongSolomon H. Snyder Department of Neuroscience, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.ORCID 0000-0002-9750-7718
Takashi TsukamotoJohns Hopkins Drug Discovery and Department of Neurology, Johns Hopkins University, Baltimore, MD 21205, USA.ORCID 0000-0002-0216-7520
Yun GuanDepartment of Anesthesiology and Critical Care Medicine, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.ORCID 0000-0003-1321-6655
Funding
Institute for Clinical and Translational ResearchUL1TR001079 · NCATS · JOHNS HOPKINS UNIVERSITY · PI FORD, DANIEL ERNEST · 2013 to 2017
$60.1M
Mrgs as New Target for the Treatment of Neuropathic PainR01NS070814 · NINDS · JOHNS HOPKINS UNIVERSITY · PI GUAN, YUN · 2011 to 2020
$3.2M
Birth Tissue Products for Non-opioid Treatment of Post-surgical PainR01NS117761 · NINDS · JOHNS HOPKINS UNIVERSITY · PI GUAN, YUN · 2020 to 2024
$2.6M
Mechanistic Study of Pain Inhibition by Activation of Non-nociceptive Afferent FibersR01NS110598 · NINDS · JOHNS HOPKINS UNIVERSITY · PI GUAN, YUN · 2019 to 2024
$2.4M
Development of MRGPRX1 positive allosteric modulators as non-addictive therapies for neuropathic painUH3NS115718 · NINDS · JOHNS HOPKINS UNIVERSITY · PI TSUKAMOTO, TAKASHI · 2021 to 2023
$2.3M
Development of MRGPRX1 positive allosteric modulators as non-addictive therapies for neuropathic painUG3NS115718 · NINDS · JOHNS HOPKINS UNIVERSITY · PI TSUKAMOTO, TAKASHI · 2019 to 2019
$1.6M
Acquisition of a 500 MHz NMR Spectrometer to Support Small-Molecule Chemistry at Johns Hopkins Medical SchoolS10OD034217 · OD · JOHNS HOPKINS UNIVERSITY · PI BHAT, SHRIDHAR · 2024 to 2024
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.
An orally bioavailable MrgprX1-positive allosteric modulator alleviates certain neuropathic pain-related behaviors in humanized mice. · full record | OpenQuestion