Evidence map›Paper›PMID 41406228›Full record

ArticleScience advances2025

High-order expansion of neural ordinary differential equation flows.

Dario Izzo, Sebastien Origer, Giacomo Acciarini, Francesco Biscani

Abstract read
In one paragraph

Article in Science advances, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Dario IzzoAdvanced Concepts Team, European Space Research and Technology Centre (ESTEC), Keplerlaan 1, 2201 AZ Noordwijk, Netherlands.ORCID 0000-0002-9846-8423
Sebastien OrigerAdvanced Concepts Team, European Space Research and Technology Centre (ESTEC), Keplerlaan 1, 2201 AZ Noordwijk, Netherlands.ORCID 0000-0003-1591-2099
Giacomo AcciariniAdvanced Concepts Team, European Space Research and Technology Centre (ESTEC), Keplerlaan 1, 2201 AZ Noordwijk, Netherlands.ORCID 0000-0001-8707-8940
Francesco BiscaniSkylon Dynamics, Kurpfalzstrasse 4a, 75053 Gondelsheim, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Artificial neural networks, widely recognized for their role in machine learning, are also transforming the study of ordinary differential equations (ODEs), bridging data-driven modeling with classical dynamical systems as well as enabling the development of infinitely deep neural models. However, their practical applicability remains, in this context, constrained by the opacity of the learned dynamics, which operate as black-box systems with limited explainability, thereby hindering trust in their deployment. Existing approaches for the analysis of neurally driven dynamical systems are now scarce and restricted to first-order gradient information due to computational constraints, thereby limiting the depth of achievable insight. Here, we introduce event transition tensors as a new tool containing high-order differential information that provides a rigorous mathematical description of NeuralODE dynamics on event manifolds. We demonstrate its versatility across diverse applications: characterizing uncertainties in a data-driven prey-predator control model, analyzing neural optimal feedback dynamics, and mapping landing trajectories in a three-body neural Hamiltonian system. In all cases, our method allows for the interpretability of NeuralODEs and their analytical verification by expressing their behavior through previously unknown explicit mathematical structures. The neural dynamics are thereby fully encapsulated within a set of compact, computationally efficient tensors, which retain all the necessary information for rigorous system analysis and certification. Our findings contribute to a deeper theoretical foundation for event-triggered neural differential equations and provide a mathematical construct for explaining complex system dynamics.

Identifiers

PMID41406228
PMCPMC12710715

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.